ID Q4DXH4_TRYCC Unreviewed; 414 AA.
AC Q4DXH4;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE SubName: Full=Pre-mRNA cleavage complex II Clp1 protein, putative {ECO:0000313|EMBL:EAN97245.1};
GN ORFNames=Tc00.1047053506941.229 {ECO:0000313|EMBL:EAN97245.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN97245.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN97245.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN97245.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN97245.1}.
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DR EMBL; AAHK01000108; EAN97245.1; -; Genomic_DNA.
DR RefSeq; XP_819096.1; XM_814003.1.
DR AlphaFoldDB; Q4DXH4; -.
DR SMR; Q4DXH4; -.
DR STRING; 353153.Q4DXH4; -.
DR PaxDb; 353153-Q4DXH4; -.
DR EnsemblProtists; EAN97245; EAN97245; Tc00.1047053506941.229.
DR GeneID; 3551454; -.
DR KEGG; tcr:506941.229; -.
DR eggNOG; KOG2749; Eukaryota.
DR InParanoid; Q4DXH4; -.
DR OMA; GENQWER; -.
DR OrthoDB; 56092at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR045116; Clp1/Grc3.
DR InterPro; IPR032319; CLP1_P.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR PANTHER; PTHR12755:SF6; POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1; 1.
DR Pfam; PF16575; CLP1_P; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 119..309
FT /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT /evidence="ECO:0000259|Pfam:PF16575"
SQ SEQUENCE 414 AA; 45270 MW; E29E72AC618064D1 CRC64;
MARGIQHAHY ELERSELNIH FKGSGCIVLV DGDATVYGAP LKRNLRYNFS WCGIPVVCSL
SCRVHVEGEF TAKICLMSSA IDDIHALLDL ARADATISND LPREFHDKGP QGPRVLVVGN
QNTGKSSLCR ALANLATSDK KYGVALVDTD VGQQGIACPG SIATAFIEEY IPVDDGFNTM
MPLIFFFGDK TVTASSRKRY LDLCAFTSQA IASVCMSKPQ YAIGGVIVNT MGWTTGIGRD
ILFELISVFS ITHVVVCGSD EDLAEELRRA AIGHSITLLR YPKQPRLFQR GRSQLCESRT
EQLLTYFKGT LRTPLSPYRG VAFVKDVYFL NALTLEVLSW QEVAPLSVAA VSWSDSLESV
DEANIAGFIV LLEIGKRFFS FLSPASGNLP KPFLLVSSTI KLPWSKVPPF TAPG
//
