ID Q4DXK9_TRYCC Unreviewed; 196 AA.
AC Q4DXK9;
DT 13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2005, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=CS domain-containing protein {ECO:0000259|PROSITE:PS51203};
GN ORFNames=Tc00.1047053506195.170 {ECO:0000313|EMBL:EAN97259.1};
OS Trypanosoma cruzi (strain CL Brener).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=353153 {ECO:0000313|EMBL:EAN97259.1, ECO:0000313|Proteomes:UP000002296};
RN [1] {ECO:0000313|EMBL:EAN97259.1, ECO:0000313|Proteomes:UP000002296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL Brener {ECO:0000313|EMBL:EAN97259.1,
RC ECO:0000313|Proteomes:UP000002296};
RX PubMed=16020725; DOI=10.1126/science.1112631;
RA El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G.,
RA Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G.,
RA Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B.,
RA Anupama A., Arner E., Aslund L., Attipoe P., Bontempi E., Bringaud F.,
RA Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H.,
RA da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G.,
RA Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y.,
RA Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J.,
RA Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y.,
RA Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M.,
RA Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L.,
RA Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J.,
RA Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C.,
RA Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D.,
RA Andersson B.;
RT "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas
RT disease.";
RL Science 309:409-415(2005).
CC -!- SIMILARITY: Belongs to the p23/wos2 family.
CC {ECO:0000256|ARBA:ARBA00025733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN97259.1}.
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DR EMBL; AAHK01000107; EAN97259.1; -; Genomic_DNA.
DR RefSeq; XP_819110.1; XM_814017.1.
DR AlphaFoldDB; Q4DXK9; -.
DR SMR; Q4DXK9; -.
DR STRING; 353153.Q4DXK9; -.
DR PaxDb; 353153-Q4DXK9; -.
DR EnsemblProtists; EAN97259; EAN97259; Tc00.1047053506195.170.
DR GeneID; 3551480; -.
DR KEGG; tcr:506195.170; -.
DR eggNOG; KOG3158; Eukaryota.
DR InParanoid; Q4DXK9; -.
DR OMA; EEGPYWP; -.
DR OrthoDB; 127050at2759; -.
DR Proteomes; UP000002296; Unassembled WGS sequence.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:InterPro.
DR CDD; cd06465; p23_hB-ind1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR045250; p23-like.
DR PANTHER; PTHR22932:SF1; CO-CHAPERONE PROTEIN DAF-41; 1.
DR PANTHER; PTHR22932; TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE; 1.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002296}.
FT DOMAIN 7..106
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 148..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 196 AA; 22176 MW; 69D39D8C1DD13B3A CRC64;
MSAGKEVVFP NILWAQRSEH VFVSIPLQDA ANVAVEIRSG RLLHFSATAG GQDYGCVLEL
FREISSEESS HVTLPRQIEL KLKKKWPNDA SDEKEVALCR AWPRLTKEKT RNCHIQVDWS
RWKDDDADSE NDGGLGFDYN NMMSEMMLQK GLEKKEPTPF SSVLEGKGEN DNQEKNDAMG
TGNNDDDYED LPPLEE
//
