ID Q4FPN7_PELUB Unreviewed; 558 AA.
AC Q4FPN7;
DT 30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:AAZ20854.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:AAZ20854.1};
GN Name=ftsI {ECO:0000313|EMBL:AAZ20854.1};
GN OrderedLocusNames=SAR11_0029 {ECO:0000313|EMBL:AAZ20854.1};
OS Pelagibacter ubique (strain HTCC1062).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Candidatus Pelagibacterales;
OC Candidatus Pelagibacteraceae; Pelagibacter.
OX NCBI_TaxID=335992 {ECO:0000313|EMBL:AAZ20854.1, ECO:0000313|Proteomes:UP000002528};
RN [1] {ECO:0000313|EMBL:AAZ20854.1, ECO:0000313|Proteomes:UP000002528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC1062 {ECO:0000313|EMBL:AAZ20854.1,
RC ECO:0000313|Proteomes:UP000002528};
RX PubMed=16109880; DOI=10.1126/science.1114057;
RA Giovannoni S.J., Tripp H.J., Givan S., Podar M., Vergin K.L., Baptista D.,
RA Bibbs L., Eads J., Richardson T.H., Noordewier M., Rappe M.S., Short J.M.,
RA Carrington J.C., Mathur E.J.;
RT "Genome streamlining in a cosmopolitan oceanic bacterium.";
RL Science 309:1242-1245(2005).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000084; AAZ20854.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4FPN7; -.
DR STRING; 335992.SAR11_0029; -.
DR KEGG; pub:SAR11_0029; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_5; -.
DR Proteomes; UP000002528; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:AAZ20854.1};
KW Cell division {ECO:0000313|EMBL:AAZ20854.1};
KW Glycosyltransferase {ECO:0000313|EMBL:AAZ20854.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002528};
KW Transferase {ECO:0000313|EMBL:AAZ20854.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..198
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 230..511
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 558 AA; 63013 MW; 136D07140DFF03F4 CRC64;
MNNKKNIILE EYENEFSYKK SKTNLDIQFN RIAFIFFVFL VISVIYSIQL LHLGSLKEEN
TKEFSTINKN YRADILDRNG NYLVKTVKSI DIGINPIEVI DKKKLLINLQ LIFPDKNYEE
ITKKLEKNKF FYLEKKISSD NYEKIMLLGD KSIKSEEKLT RIYPQKNLFS HIIGQIDDDN
KGISGLEKSF NEKLKQTNKP LKLTVDTDIQ FLIREELVKF QSIFRSKGST AILMNVNNGE
IISMVSYPDF DLNKREKIVD LNFINRATKG VYELGSVFKT FTVAAGLEEG LIDTDTEFLN
LEKKLQCGKS SISEYDNKIP SDLTVEQILI RSGNIGSVRI GQKLEIIKLK AFLEKIGILS
KINFDIEEVG EPIPFKWGKC KLATVSFGHG ITTTPLQLAK AYAIISNGGF AIEPSLIKKE
LKDPEKERRI IKAGISEKIN PILRKIVNTK EGTAGLVNIE GYEVGGKTGT AQKTIVGGYS
KAKVNTFAGI FPTSKPKYVL IVLLDEPKTS SDYVYEYKNK KGSYKGTPFN TAGWTSVEVA
GKIIEKIGPI LATKHIEN
//
