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Database: UniProt
Entry: Q4FVT3_PSYA2
LinkDB: Q4FVT3_PSYA2
Original site: Q4FVT3_PSYA2 
ID   Q4FVT3_PSYA2            Unreviewed;       481 AA.
AC   Q4FVT3;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   25-OCT-2017, entry version 100.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:AAZ17875.1};
GN   OrderedLocusNames=Psyc_0001 {ECO:0000313|EMBL:AAZ17875.1};
OS   Psychrobacter arcticus (strain DSM 17307 / 273-4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Psychrobacter.
OX   NCBI_TaxID=259536 {ECO:0000313|EMBL:AAZ17875.1, ECO:0000313|Proteomes:UP000000546};
RN   [1] {ECO:0000313|EMBL:AAZ17875.1, ECO:0000313|Proteomes:UP000000546}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17307 / 273-4 {ECO:0000313|Proteomes:UP000000546};
RX   PubMed=20154119; DOI=10.1128/AEM.02101-09;
RA   Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A.,
RA   Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M.,
RA   Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F.,
RA   Richardson P., Murray A., Thomashow M., Tiedje J.M.;
RT   "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive
RT   Siberian permafrost bacterium, reveals mechanisms for adaptation to
RT   low-temperature growth.";
RL   Appl. Environ. Microbiol. 76:2304-2312(2010).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP000082; AAZ17875.1; -; Genomic_DNA.
DR   RefSeq; WP_011279314.1; NC_007204.1.
DR   ProteinModelPortal; Q4FVT3; -.
DR   STRING; 259536.Psyc_0001; -.
DR   EnsemblBacteria; AAZ17875; AAZ17875; Psyc_0001.
DR   KEGG; par:Psyc_0001; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   HOGENOM; HOG000235659; -.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000000546; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000546};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000546}.
FT   DOMAIN      179    305       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      388    457       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     187    194       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   481 AA;  54541 MW;  1F56787576F2CA42 CRC64;
     MIDTANIWDK CLNDLRYHVK DNVFTMWLRP LSAHQENNSL IILAPNDYFV TYIKKNHLED
     IQQLVTKHSQ GSIEEVIVRV DNAGRDTDDG SSLQSGSLFA EDALPSSPAD YKFETIHHNN
     AKADIDANMR HAEMVDSADA KSLSYLNPDF TFETFVTGKS NNLAYKACYE LGKRQSKNRH
     NPLFIYGPSG LGKTHLMHSV AHRYLKNNQT FYYFTSEKFI NQLVYSLRNN KIEDFKKKIK
     KVDLLIVDDI HVLAGKTKSS NEFLTLFADF TSGDKQLILA SDRHPSQMTE FDERFRSRFS
     WGLTVAVDPP EIDTRVQILQ KKAASYGMSL PKECALFIAQ NVVSNVRRLE GALNQVFANA
     NLTGAPITLE MVQYALKDIV AMRVQAVNMD NIRKVVAEYY DVTIKDMLGR KRTRSIARPR
     QIAMALSREL TSESFPEIGQ SFGGRDHTTV MHACDKVNEL RAADPAFDKD YKTLALMLQA
     G
//
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