ID   Q4H2X2_CIOIN            Unreviewed;       744 AA.
AC   Q4H2X2; A0A1W2VQ25;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   22-FEB-2023, entry version 100.
DE   SubName: Full=Transcription factor protein {ECO:0000313|EMBL:BAE06655.1};
GN   Name=Ci-Prd-B {ECO:0000313|EMBL:BAE06655.1};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC   Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|EMBL:BAE06655.1};
RN   [1] {ECO:0000313|EMBL:BAE06655.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12736827; DOI=10.1007/s00427-003-0330-z;
RA   Satou Y., Satoh N.;
RT   "Genomewide surveys of developmentally relevant genes in Ciona
RT   intestinalis.";
RL   Dev. Genes Evol. 213:211-212(2003).
RN   [2] {ECO:0000313|EMBL:BAE06655.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15269171; DOI=10.1242/dev.01270;
RA   Imai K.S., Hino K., Yagi K., Satoh N., Satou Y.;
RT   "Gene expression profiles of transcription factors and signaling molecules
RT   in the ascidian embryo: towards a comprehensive understanding of gene
RT   networks.";
RL   Development 131:4047-4058(2004).
RN   [3] {ECO:0000313|EMBL:BAE06655.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Satou Y.;
RT   "Expressed genes in Ciona intestinalis.";
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC       ECO:0000256|RuleBase:RU000682}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB210650; BAE06655.1; -; mRNA.
DR   RefSeq; NP_001071802.1; NM_001078334.1.
DR   AlphaFoldDB; Q4H2X2; -.
DR   GeneID; 778734; -.
DR   KEGG; cin:778734; -.
DR   CTD; 778734; -.
DR   OrthoDB; 4732592at2759; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR043562; RAX/RAX2.
DR   PANTHER; PTHR46271; HOMEOBOX PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR46271:SF4; HOMEOBOX PROTEIN, PUTATIVE-RELATED; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}.
FT   DOMAIN          150..210
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        152..211
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          297..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          695..744
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..313
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        695..735
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   744 AA;  82255 MW;  4E5B208275F92CF6 CRC64;
     MSDREAVIST IAPLTSTEVC ENDPLPVNGS ADIVDSPTNL RQVIESKPGN EFSERDALYN
     KHSYSIQLGS YDGGQYCTTF PSIPNITLSN HSASRLPLQQ NGFGIPASRQ NQNIVLQDRT
     PHDHFHGFVP ETWEDSMSNI PQRCDGNGSR NLSRGRTTYS VDQITELEKL FTRNAYPTPQ
     SRQELARNIR VPEGKVKIWF QNRRARAKKQ RMLSSNSWRV GLQQTGFAPL PVRQEQSNNN
     NNSIVNEAGA AKNPAINLSS QVVPNWEYPQ GGPSQNQEGA SHTSLSLSCL SLRNQAKHNS
     LPSTTNSAAK NSAEHPPTLP LCPDNSFKFY TGSWRDVSKY ERTDFEHNEA FPSRFPVINN
     SQSHIDRSTA RFSNVASSMS PSMQSPWFQH GGYSAPAAMS SPPSAEGTGL SIATVESLSA
     PVANDKGAAT SLVTPAPHCE QHSRNKLPND ANSTGYYKGA YDLKVISSGY KANVLSGRYS
     PYLSPPTSTA LLRSPPPIRR FVFPFKNLME TSRNSVAPVG PNNVHENVDL TTRTNCAKNF
     MTLNTHTTSE AGPHFCPRQS SHCFVDSKVG SQPIDVNMAT NPNLRTLAPT FNLKPYQMQK
     NDFDTAACGT SLSKQQRFNW QMNSDRWQHI NQWNSTSSMQ KYQPQATFTS NAMHCRERSM
     PGQMWPHHQQ EYGNSKNCHV ANWPRMYPNN GSHVIETETR CPSNGSEESG SSADAQKRET
     AQGVWSVSEL IPGTQPPSSA PMVG
//