ID Q4JN11_9BACT Unreviewed; 83 AA.
AC Q4JN11;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE RecName: Full=Glutaredoxin {ECO:0000256|RuleBase:RU364065};
OS uncultured bacterium BAC13K9BAC.
OC Bacteria; environmental samples.
OX NCBI_TaxID=332979 {ECO:0000313|EMBL:AAY89986.1};
RN [1] {ECO:0000313|EMBL:AAY89986.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16008504; DOI=10.1371/journal.pbio.0030273;
RA Sabehi G., Loy A., Jung K.H., Partha R., Spudich J.L., Isaacson T.,
RA Hirschberg J., Wagner M., Beja O.;
RT "New insights into metabolic properties of marine bacteria encoding
RT proteorhodopsins.";
RL PLoS Biol. 3:E273-E273(2005).
CC -!- FUNCTION: Has a glutathione-disulfide oxidoreductase activity in the
CC presence of NADPH and glutathione reductase. Reduces low molecular
CC weight disulfides and proteins. {ECO:0000256|RuleBase:RU364065}.
CC -!- SIMILARITY: Belongs to the glutaredoxin family.
CC {ECO:0000256|ARBA:ARBA00007787, ECO:0000256|RuleBase:RU364065}.
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DR EMBL; DQ068067; AAY89986.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4JN11; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0015038; F:glutathione disulfide oxidoreductase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR CDD; cd03418; GRX_GRXb_1_3_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR014025; Glutaredoxin_subgr.
DR InterPro; IPR011900; GRX_bact.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; TIGR02181; GRX_bact; 1.
DR PANTHER; PTHR45694; GLUTAREDOXIN 2; 1.
DR PANTHER; PTHR45694:SF18; GLUTAREDOXIN-1-RELATED; 1.
DR Pfam; PF00462; Glutaredoxin; 1.
DR PRINTS; PR00160; GLUTAREDOXIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU364065};
KW Electron transport {ECO:0000256|RuleBase:RU364065};
KW Redox-active center {ECO:0000256|RuleBase:RU364065};
KW Transport {ECO:0000256|RuleBase:RU364065}.
FT DOMAIN 4..63
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
SQ SEQUENCE 83 AA; 9762 MW; C9A0DB94F85C873A CRC64;
MKKITIYSTR ICPYCVRAKN FFNKKNLEYT EIMIDRDPEQ MREMMEKSGR QSVPQIFIGD
YHVGGFDDLI EYDMDGKLEG LLG
//