ID Q4KCR8_PSEF5 Unreviewed; 439 AA.
AC Q4KCR8;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Multidrug RND efflux transporter, membrane fusion protein MdtA {ECO:0000313|EMBL:AAY92131.1};
GN Name=mdtA {ECO:0000313|EMBL:AAY92131.1};
GN OrderedLocusNames=PFL_2859 {ECO:0000313|EMBL:AAY92131.1};
OS Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=220664 {ECO:0000313|EMBL:AAY92131.1, ECO:0000313|Proteomes:UP000008540};
RN [1] {ECO:0000313|EMBL:AAY92131.1, ECO:0000313|Proteomes:UP000008540}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5
RC {ECO:0000313|Proteomes:UP000008540};
RX PubMed=15980861; DOI=10.1038/nbt1110;
RA Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.,
RA Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S.III.,
RA Thomashow L.S., Loper J.E.;
RT "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT Pf-5.";
RL Nat. Biotechnol. 23:873-878(2005).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000076; AAY92131.1; -; Genomic_DNA.
DR RefSeq; WP_011061149.1; NC_004129.6.
DR AlphaFoldDB; Q4KCR8; -.
DR STRING; 220664.PFL_2859; -.
DR KEGG; pfl:PFL_2859; -.
DR PATRIC; fig|220664.5.peg.2911; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_0_6; -.
DR Proteomes; UP000008540; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF12; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 97..144
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 45..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 46932 MW; 46DA988CC501F984 CRC64;
MVDHSMQSSV SRNSRRWLFG LFVLLLVVGL CWKFWPASTH QEAAGQKAAT GHTGRSGSMR
PGFGGASGPI PVRVSPVTQG DFAVYYKALG TVTALNTINV RSRVAGELVK VNFEEGQMVK
AGDLLAQIDP RPYQNALLQA EGTLLQNQAQ LKNAQVDLER YRGLYAQDSI AKQTLDTAAA
LVGQYQGTVK TNQAAVNDAK LNLEFTNIRA PIAGRLGLRQ LDVGNLVAAN DTTALVIITQ
TQPISVAFTL PENSLETVLA RYHSGARLAV EAWDRGDVKL QATGVLQSLD NQIDTTTGTL
KFKARFDNRD QGLFPNQFVN VRLLADTLKN VVLAPSAAIQ FGTNGTFVYA LDGDNKVKIR
QLKVGASNGD STVIQDGLKA GDRVVMEGTD RLKDGSEVEV VNDSIDVPTT PTEHLQGQPA
GAPAADGKPA DGKAQKVGA
//
