ID Q4L914_STAHJ Unreviewed; 475 AA.
AC Q4L914;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 126.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN OrderedLocusNames=SH0552 {ECO:0000313|EMBL:BAE03861.1};
OS Staphylococcus haemolyticus (strain JCSC1435).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=279808 {ECO:0000313|EMBL:BAE03861.1, ECO:0000313|Proteomes:UP000000543};
RN [1] {ECO:0000313|EMBL:BAE03861.1, ECO:0000313|Proteomes:UP000000543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCSC1435 {ECO:0000313|EMBL:BAE03861.1,
RC ECO:0000313|Proteomes:UP000000543};
RX PubMed=16237012; DOI=10.1128/JB.187.21.7292-7308.2005;
RA Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA Hiramatsu K.;
RT "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT extreme plasticity of its genome and the evolution of human-colonizing
RT staphylococcal species.";
RL J. Bacteriol. 187:7292-7308(2005).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; AP006716; BAE03861.1; -; Genomic_DNA.
DR RefSeq; WP_011274877.1; NC_007168.1.
DR AlphaFoldDB; Q4L914; -.
DR KEGG; sha:SH0552; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_0_9; -.
DR Proteomes; UP000000543; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07088; ALDH_LactADH-AldA; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 11..467
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 247
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 475 AA; 52276 MW; B0D5252A99A649DF CRC64;
MTNQLFINNE FVESKSNDTM EVINPATGEA FDTITFATEE EVNEAIEKSK HAQLEWEKVP
APTRAEHVKL LIPLLEQNKD ELAKLYVKEQ GKTLAQAEGE IDKAVQFIDY MTSLSMRNKG
EVLQNSVSHE MIQLIKKPIG VTAGIVPWNA PIMVLMRKVI PALVTGCSIV IKPSEETTLL
TLRLAELFRA STIPAGLVQI VPGTGETVGT QLATHKDVQL ISLTGSMRAG KAVYKNAADT
VKKVNLELGG NAPVLVTPHA NLDKAVDYIV TARINNAGQV CTCPERIFVH EDVHDDFVSK
AKQRMSDLQV GDPLDDNTDY GAIINQTQLD SIDNKVQEAI KNGADLVLGG HKLDRAGFFY
EPTILDNVKK DDSAFKEEIF GPVLAITTYN DFDEAIDAAN DTNAGLSSYI FSENLKEVME
ATERLKFGEV YANCEAEEVV NGYHAGWRES GLGGADGIHG FEEYYNTTVS YIRYE
//
