ID Q4N877_THEPA Unreviewed; 382 AA.
AC Q4N877;
DT 02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT 02-AUG-2005, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Translation initiation factor eIF2B subunit gamma {ECO:0000256|ARBA:ARBA00044196};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit gamma {ECO:0000256|ARBA:ARBA00044229};
GN OrderedLocusNames=TP01_0593 {ECO:0000313|EMBL:EAN33831.1};
OS Theileria parva (East coast fever infection agent).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=5875 {ECO:0000313|EMBL:EAN33831.1};
RN [1] {ECO:0000313|EMBL:EAN33831.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Muguga {ECO:0000313|EMBL:EAN33831.1};
RX PubMed=15994558; DOI=10.1126/science.1110439;
RA Gardner M.J., Bishop R., Shah T., de Villiers E.P., Carlton J.M., Hall N.,
RA Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA Lynn J., Weaver B., Shoaibi A., Domingo A.R., Wasawo D., Crabtree J.,
RA Wortman J.R., Haas B., Angiuoli S.V., Creasy T.H., Lu C., Suh B.,
RA Silva J.C., Utterback T.R., Feldblyum T.V., Pertea M., Allen J.,
RA Nierman W.C., Taracha E.L.N., Salzberg S.L., White O.R., Fitzhugh H.A.,
RA Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RT "Genome sequence of Theileria parva, a bovine pathogen that transforms
RT lymphocytes.";
RL Science 309:134-137(2005).
RN [2] {ECO:0000313|EMBL:EAN33831.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Muguga {ECO:0000313|EMBL:EAN33831.1};
RA Gardner M., Bishop R., Shah T., de Villiers E., Carlton J.M., Hall N.,
RA Ren Q., Paulsen I.T., Pain A., Berriman M., Wilson R.J.M., Sato S.,
RA Ralph S.A., Mann D.J., Xiong Z., Shallom S.J., Weidman J., Jiang L.,
RA Lynn J., Weaver B., Shoaibi A., Wasawo D., Crabtree J., Wortman J.R.,
RA Haas B., Angiuoli S., Creasy T.H., Lu C., Suh B., Silva J.C., Utterback T.,
RA Feldblyum T., Pertea M., Allen J., Taracha E.L., Salzberg S.L., White O.,
RA Fitzhugh H.A., Morzaria S., Venter J.C., Fraser C.M., Nene V.;
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC {ECO:0000256|ARBA:ARBA00007878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAN33831.1}.
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DR EMBL; AAGK01000001; EAN33831.1; -; Genomic_DNA.
DR RefSeq; XP_766114.1; XM_761021.1.
DR AlphaFoldDB; Q4N877; -.
DR STRING; 5875.Q4N877; -.
DR EnsemblProtists; EAN33831; EAN33831; TP01_0593.
DR GeneID; 3502528; -.
DR KEGG; tpv:TP01_0593; -.
DR VEuPathDB; PiroplasmaDB:TpMuguga_01g02835; -.
DR eggNOG; KOG1462; Eukaryota.
DR InParanoid; Q4N877; -.
DR OMA; NCVINPK; -.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR45989; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR PANTHER; PTHR45989:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 17..158
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 382 AA; 42847 MW; F4FC321099A1A48B CRC64;
MGDKSSSECS LPYDVTAVVL SGGSSNNFIS LTQSLPKILL KVGSNTLLYH TVRNLIINQF
KEIIILTSEN ISSLVDENLR VSLNFLRDEF GSEKLPKVSV MGVPTSDDSS FGSTDSLNYI
SEHIKNDFVV LPCDLFGNFD FKSFLLDHLK SPRLCTVALL DINSLGSAKA KKEVCLGGND
FEDWSFKYRV VTALDKSTCS LLSIAPHLSV ESGESFQLFR YHLVNHANSL ITFDLVDIHV
YSFSINIFKV LRCDFLLNSS IRRYTIYTIV QHTVEYLKND NFESLQHELE NCSDKSWKLS
DVVFDEFLER TRTFYFIASG ESFNCSRVNS IDSLYSANIK CSLTSKEKIA KKTPKIKNVL
LGNSSEVSES AEIKNSVIGE LN
//
