ID DBP9_USTMA Reviewed; 686 AA.
AC Q4P7M1;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-APR-2013, entry version 55.
DE RecName: Full=ATP-dependent RNA helicase DBP9;
DE EC=3.6.4.13;
GN Name=DBP9; ORFNames=UM03892;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T.,
RA Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O.,
RA Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J.,
RA Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.,
RA Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W.,
RA Guzman P., Farman M.L., Stajich J.E., Sentandreu R.,
RA Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M.,
RA Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U.,
RA Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W.,
RA Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K.,
RA Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen
RT Ustilago maydis.";
RL Nature 444:97-101(2006).
CC -!- FUNCTION: ATP-binding RNA helicase involved in the biogenesis of
CC 60S ribosomal subunits and is required for the normal formation of
CC 25S and 5.8S rRNAs (By similarity).
CC -!- CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus (By similarity).
CC -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC box family of RNA helicases and controls ATP binding and
CC hydrolysis.
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX56/DBP9
CC subfamily.
CC -!- SIMILARITY: Contains 1 helicase ATP-binding domain.
CC -!- SIMILARITY: Contains 1 helicase C-terminal domain.
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DR EMBL; AACP01000132; EAK85065.1; -; Genomic_DNA.
DR RefSeq; XP_760039.1; XM_754946.1.
DR ProteinModelPortal; Q4P7M1; -.
DR STRING; 5270.UM03892.1; -.
DR EnsemblFungi; UM03892T0; UM03892P0; UM03892.
DR GeneID; 3631977; -.
DR KEGG; uma:UM03892.1; -.
DR eggNOG; COG0513; -.
DR HOGENOM; HOG000253015; -.
DR KO; K14810; -.
DR OMA; TFLMSAT; -.
DR OrthoDB; EOG4DFSWQ; -.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR000560; His_Pase_superF_clade-2.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; FALSE_NEG.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Helicase; Hydrolase;
KW Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW RNA-binding; rRNA processing.
FT CHAIN 1 686 ATP-dependent RNA helicase DBP9.
FT /FTId=PRO_0000232346.
FT DOMAIN 90 275 Helicase ATP-binding.
FT DOMAIN 288 543 Helicase C-terminal.
FT NP_BIND 103 110 ATP (By similarity).
FT MOTIF 59 87 Q motif.
FT MOTIF 221 224 DEAD box.
SQ SEQUENCE 686 AA; 75202 MW; C7F924882EF3AFF8 CRC64;
MSEPSSSKVK ADSLLPPAKS TTAATAARSA NGSTNTGASQ LTKHGIELPS QEDAERLGFN
VFSHILDPRL LRALADLGYG IPTPIQQKAI PLALAGKDIL ARARTGSGKT LAYGLPLLQK
VLDAKSAVAK SDANHQLTRA LVLVPTRELA EQVFRHLSVV IEYVRDDIRL VNVAREASEK
VQRLLLSEKP DVVIATPSKA LNYLQNASLD LKSGMESLAI DEADLILSYG HDADVKSLLG
ANFLPSHFQS FLMSATMTSD VSKLKGLLLR NPVVLKLNHD DEAASGSNLV QFYTKTTEED
KFLLAYVILK LKLIRGKAIL FVNELERGYR LKLFLEKFGL RACVLNAELP INSRYSIVEE
FNKGKFDYIV ATDEPTGASG NMQDDEGDDE EEDADEREAD EVDEQAEDQR EAGKKRKSSE
HAGAETKSNK SKVSQHRKGK NGASEYGVSR GVDFINVSCV INFDLPTSVD SYIHRVGRTA
RGGASGTALS FVVPSDQVGR SKYLYCASTT RDESVFKMLN KPSTISLLGS ALQEWKYDSS
SVAGFHYRVT DTLKSITKAL IREARIKELK NEILTSSKLQ SHFEDHPDDL AFLQHDKALL
TSRAQQSHLK HVPQYLVPKI INPGAKLTKS SGSEYKGYVP KNKIKDGAND RKNKGGKRRS
STGKNTTGAA GKSRKKVDPL RKFSNK
//
