ID Q4Q6C9_LEIMA Unreviewed; 461 AA.
AC Q4Q6C9;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 03-MAY-2023, entry version 89.
DE RecName: Full=CSD domain-containing protein {ECO:0000259|PROSITE:PS51857};
GN ORFNames=LMJF_31_1340 {ECO:0000313|EMBL:CAJ08321.1};
OS Leishmania major.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5664 {ECO:0000313|EMBL:CAJ08321.1, ECO:0000313|Proteomes:UP000000542};
RN [1] {ECO:0000313|EMBL:CAJ08321.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=16020728; DOI=10.1126/science.1112680;
RA Ivens A.C., Peacock C.S., Worthey E.A., Murphy L., Aggarwal G.,
RA Berriman M., Sisk E., Rajandream M.A., Adlem E., Aert R., Anupama A.,
RA Apostolou Z., Attipoe P., Bason N., Bauser C., Beck A., Beverley S.M.,
RA Bianchettin G., Borzym K., Bothe G., Bruschi C.V., Collins M., Cadag E.,
RA Ciarloni L., Clayton C., Coulson R.M., Cronin A., Cruz A.K., Davies R.M.,
RA De Gaudenzi J., Dobson D.E., Duesterhoeft A., Fazelina G., Fosker N.,
RA Frasch A.C., Fraser A., Fuchs M., Gabel C., Goble A., Goffeau A.,
RA Harris D., Hertz-Fowler C., Hilbert H., Horn D., Huang Y., Klages S.,
RA Knights A., Kube M., Larke N., Litvin L., Lord A., Louie T., Marra M.,
RA Masuy D., Matthews K., Michaeli S., Mottram J.C., Muller-Auer S.,
RA Munden H., Nelson S., Norbertczak H., Oliver K., O'neil S., Pentony M.,
RA Pohl T.M., Price C., Purnelle B., Quail M.A., Rabbinowitsch E.,
RA Reinhardt R., Rieger M., Rinta J., Robben J., Robertson L., Ruiz J.C.,
RA Rutter S., Saunders D., Schafer M., Schein J., Schwartz D.C., Seeger K.,
RA Seyler A., Sharp S., Shin H., Sivam D., Squares R., Squares S., Tosato V.,
RA Vogt C., Volckaert G., Wambutt R., Warren T., Wedler H., Woodward J.,
RA Zhou S., Zimmermann W., Smith D.F., Blackwell J.M., Stuart K.D.,
RA Barrell B., Myler P.J.;
RT "The genome of the kinetoplastid parasite, Leishmania major.";
RL Science 309:436-442(2005).
RN [2] {ECO:0000313|EMBL:CAJ08321.1, ECO:0000313|Proteomes:UP000000542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/IL/81/Friedlin {ECO:0000313|Proteomes:UP000000542};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
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DR EMBL; FR796427; CAJ08321.1; -; Genomic_DNA.
DR RefSeq; XP_001685119.1; XM_001685067.1.
DR AlphaFoldDB; Q4Q6C9; -.
DR EnsemblProtists; CAJ08321; CAJ08321; LMJF_31_1340.
DR GeneID; 5654064; -.
DR KEGG; lma:LMJF_31_1340; -.
DR VEuPathDB; TriTrypDB:LmjF.31.1340; -.
DR VEuPathDB; TriTrypDB:LMJFC_310022500; -.
DR VEuPathDB; TriTrypDB:LMJLV39_310020400; -.
DR VEuPathDB; TriTrypDB:LMJSD75_310019900; -.
DR eggNOG; ENOG502S8Z2; Eukaryota.
DR HOGENOM; CLU_593777_0_0_1; -.
DR InParanoid; Q4Q6C9; -.
DR OMA; MQMEGFR; -.
DR Proteomes; UP000000542; Chromosome 31.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR002059; CSP_DNA-bd.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR Pfam; PF00313; CSD; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS51857; CSD_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000542}.
FT DOMAIN 334..446
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT REGION 250..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 47824 MW; FC2CB4E764015F87 CRC64;
MFRAVYSNPA ANVPASNCMT DGFPLLPPQR PHSSGSQLMR GCPLPWNDGR TLMYGVPAKN
EASLQQVSYS RTLGQRWSSG SADNAAQCAA ATHSTVCFAS CASGANGSAG GSPVLLQPAM
GVPAFVTDNQ QLPSMVAQSS PTVSRLTSGM CSTSEGSATF GASTTSATSS TVGNCAATGT
AATTNGSMAH TGTSPALPGF QMSVPLPTSA MTAVAAPPQQ PQTCFWLSHT TGALTPIRKE
DMMTISDTSA STNTHSYAMP PPPTMPSQPS SASATSVPTY LMAPQVSSFG GAMVQAFSEL
LSGSTAFSVP ALPLPQPPRP PKTLNGLQYH LGELYEGFVK RYNPNRGFGF LTATTHVTVV
NDGSNSDSAT GTPIASLNNT TTAVPTTGEA ETPKEYRTPV HLGDIFVHQS SMQMEGFRTL
PVGGRVRFCI GYKDGQQTLQ AVNVELLPQV LPPNVEMASS P
//
