ID Q4QLZ2_HAEI8 Unreviewed; 800 AA.
AC Q4QLZ2;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE RecName: Full=Outer membrane protein assembly factor BamA {ECO:0000256|HAMAP-Rule:MF_01430};
DE Flags: Precursor;
GN Name=bamA {ECO:0000256|HAMAP-Rule:MF_01430};
GN OrderedLocusNames=NTHI1084 {ECO:0000313|EMBL:AAX87955.1};
OS Haemophilus influenzae (strain 86-028NP).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=281310 {ECO:0000313|EMBL:AAX87955.1, ECO:0000313|Proteomes:UP000002525};
RN [1] {ECO:0000313|EMBL:AAX87955.1, ECO:0000313|Proteomes:UP000002525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=86-028NP {ECO:0000313|EMBL:AAX87955.1,
RC ECO:0000313|Proteomes:UP000002525};
RX PubMed=15968074; DOI=10.1128/JB.187.13.4627-4636.2005;
RA Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA Munson R.S.Jr.;
RT "Genomic sequence of an otitis media isolate of nontypeable Haemophilus
RT influenzae: comparative study with H. influenzae serotype d, strain KW20.";
RL J. Bacteriol. 187:4627-4636(2005).
CC -!- FUNCTION: Part of the outer membrane protein assembly complex, which is
CC involved in assembly and insertion of beta-barrel proteins into the
CC outer membrane. {ECO:0000256|HAMAP-Rule:MF_01430}.
CC -!- SUBUNIT: Part of the Bam complex. {ECO:0000256|HAMAP-Rule:MF_01430}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01430}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC -!- SIMILARITY: Belongs to the BamA family. {ECO:0000256|HAMAP-
CC Rule:MF_01430}.
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DR EMBL; CP000057; AAX87955.1; -; Genomic_DNA.
DR RefSeq; WP_011272286.1; NC_007146.2.
DR AlphaFoldDB; Q4QLZ2; -.
DR KEGG; hit:NTHI1084; -.
DR HOGENOM; CLU_007664_1_0_6; -.
DR Proteomes; UP000002525; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.20.310; membrane protein fhac; 5.
DR Gene3D; 2.40.160.50; membrane protein fhac: a member of the omp85/tpsb transporter family; 1.
DR HAMAP; MF_01430; OM_assembly_BamA; 1.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR010827; BamA/TamA_POTRA.
DR InterPro; IPR039910; D15-like.
DR InterPro; IPR023707; OM_assembly_BamA.
DR InterPro; IPR034746; POTRA.
DR NCBIfam; TIGR03303; OM_YaeT; 1.
DR PANTHER; PTHR12815:SF23; OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMA; 1.
DR PANTHER; PTHR12815; SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF01103; Omp85; 1.
DR Pfam; PF07244; POTRA; 4.
DR PIRSF; PIRSF006076; OM_assembly_OMP85; 1.
DR PROSITE; PS51779; POTRA; 5.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|HAMAP-Rule:MF_01430};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01430};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|HAMAP-Rule:MF_01430};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01430};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01430};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452,
KW ECO:0000256|HAMAP-Rule:MF_01430}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01430"
FT CHAIN 20..800
FT /note="Outer membrane protein assembly factor BamA"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01430"
FT /id="PRO_5009019219"
FT DOMAIN 22..89
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 90..170
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 173..259
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 262..341
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
FT DOMAIN 344..418
FT /note="POTRA"
FT /evidence="ECO:0000259|PROSITE:PS51779"
SQ SEQUENCE 800 AA; 87943 MW; C135D015140B7B27 CRC64;
MKKLLIASLL FGTTTTVFAA PFVAKDIRVD GVQGDLKQQI RASLPVRAGQ RVTDNDVANI
VRSLFVSGRF DDVKAHQEGD VLVVSVVAKS IISDVKIKGN SIIPTEALKQ NLDANGFKVG
DVLIREKLNE FAKSVKEHYA SVGRYNATVE PIVNTLPNNR AEILIQINED DKAKLASLTF
KGNESVSSST LQEQMELQPD SWWKLWGNKF EGAQFEKDLQ SIRDYYLNNG YAKAQITKTD
VQLNDEKTKV NVTIDVNEGL QYDLRSARII GNLGGMSAEL EPLLSALHLN DTFRRSDIAD
VENAIKAKLG ERGYGSATVN SVPDFDDANK TLAITLVVDA GRRLTVRQLR FEGNTVSADS
TLRQEMRQQE GTWYNSQLVE LGKIRLDRTG FFETVENRID PINGSNDEVD VVYKVKERNT
GSINFGIGYG TESGISYQAS VKQDNFLGTG AAVSIAGTKN DYGTSVNLGY TEPYFTKDGV
SLGGNVFFEN YDNSKSDTSS NYKRTTYGSN VTLGFPVNEN NSYYVGLGHT YNKISNFALE
YNRNLYIQSM KFKGNGIKTN DFDFSFGWNY NSLNRGYFPT KGVKASLGGR VTIPGSDNKY
YKLSADVQGF YPLDRDHLWV VSAKASAGYA NGFGNKRLPF YQTYTAGGIG SLRGFAYGSI
GPNAIYAAQN GNSNSNSNGT FNKISSDVIG GNAITTASAE LIVPTPFVSD KSQNTVRTSL
FVDAASVWNT KWKSDKSGLD NNVLKSLPDY GKSSRIRAST GVGFQWQSPI GPLVFSYAKP
IKKYENDDVE QFQFSIGGSF
//
