ID   Q4R6J6_MACFA            Unreviewed;       313 AA.
AC   Q4R6J6;
DT   19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Testis cDNA, clone: QtsA-17881, similar to human map kinase phosphatase-like protein MK-STYX (MK-STYX),mRNA, RefSeq: NM_016086.2 {ECO:0000313|EMBL:BAE01279.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|EMBL:BAE01279.1};
RN   [1] {ECO:0000313|EMBL:BAE01279.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15944441; DOI=10.1093/molbev/msi187;
RA   Osada N., Hirata M., Tanuma R., Kusuda J., Hida M., Suzuki Y., Sugano S.,
RA   Gojobori T., Shen C.K., Wu C.I., Hashimoto K.;
RT   "Substitution rate and structural divergence of 5'UTR evolution:
RT   comparative analysis between human and cynomolgus monkey cDNAs.";
RL   Mol. Biol. Evol. 22:1976-1982(2005).
RN   [2] {ECO:0000313|EMBL:BAE01279.1}
RP   NUCLEOTIDE SEQUENCE.
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AB169187; BAE01279.1; -; mRNA.
DR   RefSeq; NP_001271559.1; NM_001284630.1.
DR   AlphaFoldDB; Q4R6J6; -.
DR   OrthoDB; 5382152at2759; -.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14517; DSP_STYXL1; 1.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR   PANTHER; PTHR46659; SERINE/THREONINE/TYROSINE-INTERACTING-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR46659:SF1; SERINE_THREONINE_TYROSINE-INTERACTING-LIKE PROTEIN 1; 1.
DR   Pfam; PF00782; DSPc; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   SMART; SM00195; DSPc; 1.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   2: Evidence at transcript level;
KW   Kinase {ECO:0000313|EMBL:BAE01279.1};
KW   Transferase {ECO:0000313|EMBL:BAE01279.1}.
FT   DOMAIN          159..302
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50054"
SQ   SEQUENCE   313 AA;  35833 MW;  ABFA3F1FE2BA5E41 CRC64;
     MPGLLLCEPT ELYNILNQAT KLSRSTEPNY LCLFDVRSKW EYDESHVITA LRVKKKNNEY
     LLPESVDLEC VKYCVVNDNN TSTLEVLLKD DDDDSDSDSA GKDVVPGAAI EYGRILTRLT
     RHPVYILKGG YERFSGTYHF LRTQKIIWMP QELDAFQPYP IEIMPGEVFL GNFSQACDPK
     IQKDLKIKAH VNVSMDTGPF FAGDPDRLLH IRIEDAPEAQ ILPFLRHVCH FIDVHRHLGS
     VILIFSTQGI SRSCATVIAY LMHYNEQTLQ RSWAYVKKCK NNMCPNRGLV SQLLEWEKTI
     LGDSVTNIMD PLY
//