ID   Q4RG05_TETNG            Unreviewed;       589 AA.
AC   Q4RG05;
DT   19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   19-JUL-2005, sequence version 1.
DT   03-APR-2013, entry version 56.
DE   SubName: Full=Chromosome undetermined SCAF15108, whole genome shotgun sequence.;
DE   Flags: Fragment;
GN   ORFNames=GSTENG00035077001;
OS   Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS   nigroviridis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;
OC   Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;
OC   Tetradontoidea; Tetraodontidae; Tetraodon.
OX   NCBI_TaxID=99883;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15496914; DOI=10.1038/nature03025;
RA   Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA   Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A.,
RA   Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B.,
RA   Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S.,
RA   Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B.,
RA   Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V.,
RA   Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J.,
RA   Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S.,
RA   Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J.,
RA   Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M.,
RA   Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C.,
RA   Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT   "Genome duplication in the teleost fish Tetraodon nigroviridis reveals
RT   the early vertebrate proto-karyotype.";
RL   Nature 431:946-957(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RG   Genoscope;
RG   Whitehead Institute Centre for Genome Research;
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily.
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DR   EMBL; CAAE01015108; CAG12677.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q4RG05; -.
DR   STRING; 99883.ENSTNIP00000022136; -.
DR   eggNOG; COG0515; -.
DR   HOGENOM; HOG000224564; -.
DR   HOVERGEN; HBG054502; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IEA:GOC.
DR   InterPro; IPR000333; Activin_II/TGFBeta-II_recpt.
DR   InterPro; IPR000472; Activin_rcpt.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR003605; TGF_beta_rcpt_GS.
DR   Pfam; PF01064; Activin_recp; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF08515; TGF_beta_GS; 1.
DR   PRINTS; PR00653; ACTIVIN2R.
DR   SMART; SM00467; GS; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   PROSITE; PS51256; GS; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Serine/threonine-protein kinase.
FT   NON_TER       1      1
SQ   SEQUENCE   589 AA;  65296 MW;  4259250DA9E1E444 CRC64;
     LLSLSPGLQC YCDRCSANSS CVTDGVCFVA IRRSGSHQTT EQRQCVHKKE LIPWDRPFIC
     APSVKDDTGV YPMCCTSDYC NKEHKLPVSP PEVRPLGPVA LAAVIAGPVC VLCLLLVLAF
     YICHNHRGLG AGGAGAHHHH HRVPNEEDPS MDHPFITVGT TLKDLIYDMT TSGSGSGLPL
     LVQRTIARTI ILQESIGKGR FGEVWRGKWR GEEVAVKIFS SREERSWFRE AEIYQTVMLR
     HENILGFIAA DNKDNGTWTQ LWLVSDYHEH GSLFDYLNRY TVTVEGMIKL SLSTASGLAH
     LHMEIVGTQG KPAIAHRDLK SKNILVKKNG TCCIADLGLA VRHDSATDTI DIAPNHRVGT
     KRYMAPEVLD DSINMKHFES FKRADIYAMG LVFWEVANRC SMGGIHEDYQ LPYYDLVQSD
     PSVEEMRKVV CEQKLRPNIP NRWQSCEVGL PQVLGSAHRP VWTCLVSECR RKLGDGWRLN
     LSSSSVGNHT ALLDEDPTSS QGQEDPHMVP SDRGLTGDGK DNEGVLVCQQ RRAPDCSPDQ
     KDAVPAQPAG GDQDVAAERQ RADSHLHPHH QRSGLHPGSV SFPLRFSLL
//