ID Q4RLR1_TETNG Unreviewed; 1741 AA.
AC Q4RLR1;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=(spotted green pufferfish) hypothetical protein {ECO:0000313|EMBL:CAG10671.1};
GN ORFNames=GSTENG00032379001 {ECO:0000313|EMBL:CAG10671.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG10671.1};
RN [1] {ECO:0000313|EMBL:CAG10671.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG10671.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG10671.1}.
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DR EMBL; CAAE01015019; CAG10671.1; -; Genomic_DNA.
DR KEGG; tng:GSTEN00032379G001; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013662; RIH_assoc-dom.
DR InterPro; IPR015925; Ryanodine_IP3_receptor.
DR InterPro; IPR009460; Ryanrecept_TM4-6.
DR PANTHER; PTHR46399; B30.2/SPRY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46399:SF9; RYANODINE RECEPTOR 3; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08454; RIH_assoc; 1.
DR Pfam; PF06459; RR_TM4-6; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 971..991
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1199..1219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1262..1285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1428..1446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1458..1482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1570..1592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 735..761
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 896..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..925
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1121..1169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG10671.1"
SQ SEQUENCE 1741 AA; 199223 MW; 7693C64ACA7E4406 CRC64;
MTTPLFSRKS CDLVFLSGGQ DQERRHKKRR GEFYSVQTSL IVAALKKMLP IGLNMCTPGD
QELISLAKMR YLLKDTDEEV KDHIQQNLHL REKSEDPAVR WQLNLYRDRA LRFEGPPDPE
KVLDRIQRIS AAVFNLEQVE QPLRSKKCVW QKLLSKQRKR AVVACFRMAP LYNLPRHRSI
NLFLQAYQRI WIETEEYSFE EKLVQDLAKI QPKIEEEEEE EVRKQPDPLH QLILHFSHNA
LTECSSLEED PLYIAYADMM AKSCAEGEEE EEEKEKTFEV GKLLLCMAGL FLFSSFEIWL
TVLSLMQEKE MEKQKMLYQQ ARLHDRGAAE MVLQMISASK GGELRFFFLC APFLTRSVCG
LSSPGRLGAM VTVTLKLGIS ILNGGNILVQ QKMLDYLKEK RDVGFFKSLS GLMMSCSVLD
LNAFERQNKA EGLGMVTEEG SSSKVLQDDE FTKDLFRFLQ LLCEGHNNGR FDIKLTVSVF
VTMPRNLTFS FVLDFQNFLR TQTGNTTTVN IIISTVDYLL RLQESISDFY WYYSGKDVID
EAGQRNFSRA LAVAKQVFNS LTEYIQGPCV GNQQSLAHSR LWDAVVGFLH VFANMQMKLS
QDLGQACPTL SLSGVNSVFV LSGQDSSQIE LLKELLDLQQ DMIVMMLSLL EGSLFELYSI
EPKARLISLF GMLLLLFFVC GHHTCVRFIV GNVVNGTIGK QMVDTLVESS SNVEMILKFF
DMFLKLKDLT TSDSFKEYDP ENKGVISKKD FQKSMENQKQ YSQSEIEFLL SCAEADENDM
FNYKQFVDRF HEPAKDIGFN VAVLLTNLSE HMPHDARLST FLDLAESVLS YFEPYLGRIE
IMGGAKRIER VYFEISESSR TQWEKPQRGE SEKMELFVNF CEDTIFEMQL ASQISEPDPV
ERAEEDEDDG QSVQENQEEE EEQSVLLESS SAFTVACISM RKSLCHFRQL LTLRSLRRQY
RTFRKMTVRE MVQGFFSFFW IIITGFLHFF YSLVWGFFHI LWTTMFGGGF VEGAKNMKVT
DILGNMPDPT QFGIHGDVLE LEKIEANEAS ALADIGQMSQ GDAAEAALMA ELLNVQPRKE
GKHGSEPGLG DVSEVVVGDA PSIASAVKQK KAQMAAKKTA SNGEHKSDLE KVDSEYGEKN
DHVRTKDEAP QGSSVEEKKA PKKRLGQRKE PPEAFMASFF ASVEIYQTKI LNYLARNFYN
LRFLALFVAF AINFILLFYK VTGDYSDEED LWNGRRRTGG EEEEEGALEY FILQESTGYM
APALRCLAIL HTIISFLCVV GYYYLKVPLV VFKREKEIAR KLEFAGLYIT EQPSDDDIKG
QWDRLVINTP SFPNNYWDKF VKRKVIKKYG DLYGAERIAE LLGLDKSALD FNPTEETVTK
EASLVSWLSS IDTKYHVWKM GVVFTDNVSW NRGSERVKRT RVFLTENANA LLSLLLSQSF
LYLVWYTTMS ILGHYNNFFF AAHLLDIAMG FKTLRTILSS VTHNGKQVRR RRAGTDGGPV
GSRGLSLHGG GLQLLQKVYN KSEDEDEPDM KCDDMMTCYL FHMYVGVRAG GGIGDEIEDP
AGDPYELYRI LFDITFFFFV IVILLAIIQG ALRVIQQFHL TQSAFYEAVC FCARRSDHRC
LWRAERSAGT SQRGHGGEAG GKERNIRSQE PFGDALFRLQ TKCFICGIGN DYFDTTPHGF
ETHTLQEHNL ANYLFFLMYL INKDETEHTG QESYVWKMYQ ERCWDFFPAG DCFRKQYEDQ
L
//
