ID Q4RTB1_TETNG Unreviewed; 1081 AA.
AC Q4RTB1;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=(spotted green pufferfish) hypothetical protein {ECO:0000313|EMBL:CAG08371.1};
GN ORFNames=GSTENG00029334001 {ECO:0000313|EMBL:CAG08371.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG08371.1};
RN [1] {ECO:0000313|EMBL:CAG08371.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG08371.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CNKSR family.
CC {ECO:0000256|ARBA:ARBA00009498}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG08371.1}.
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DR EMBL; CAAE01014998; CAG08371.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4RTB1; -.
DR KEGG; tng:GSTEN00029334G001; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01260; PH_CNK_mammalian-like; 1.
DR CDD; cd09511; SAM_CNK1_2_3-suppressor; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR049628; CNK1-3_SAM.
DR InterPro; IPR010599; CNK2/3_dom.
DR InterPro; IPR017874; CRIC_domain.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF12; CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 2; 1.
DR Pfam; PF06663; CNK2_3_dom; 1.
DR Pfam; PF10534; CRIC_ras_sig; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51290; CRIC; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
FT DOMAIN 11..76
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 77..171
FT /note="CRIC"
FT /evidence="ECO:0000259|PROSITE:PS51290"
FT DOMAIN 208..289
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 565..664
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 393..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 473..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..761
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..848
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1081 AA; 121889 MW; AADFC362B1296587 CRC64;
MALVMEPISK WTPKQVLDWM KGLDDCLQQY VKNFEREQMG GEQLLHITHQ ELEELGVTRI
GHQELILEAN YGLETENLRT LSHKLNASAK NLQNFILGRR RGGHYDGRAS RRLPNDFLTS
VVDLIGAAKN LLAWLDRSPF SSVTEYSLLK NNIVQLCLEL TTIVQQDCTV YETENKILHV
CKTLAGICDH IISLSSDSLV SQSAHLEVVH LTSIPPSEGL GMYIKSTYDG LHVITGTTEN
SPADQCKKIH AGDEVIQVNH QTVGWQLKNL VNALREDPCG VILTLKKRPQ NTLSSTPALL
RNVRWKPLGL QPVPTSPTST SPTPGGTLGM SKMDAPSMQD VYILSPVSGL YSTREELGLM
SCDDISRYSL SSQSGSKGSE TVSYYLDQDS GQFFSLLEGD GPPGPEYDRG RNTGVRRRDK
TPTHGDLRPV SMPPEYNWMA EAKDPSMGKR GSRDSDNSLL RYLSDDKILV IEEEPEVPSR
ESRRDSTRRS RRKSRNPSSP SFPISPSMLS STLRLDQPPD ALPVRTESIA NSFHYTSLRT
KTKRRSKGSL TSASRRRISC KDLGHGDCEG WLWKKKDAKG YFTQKWRKYW FILKESCLYW
YTNQNDEKAE GFISLPEFRI DRAIECRRKF AFKACHPKIK SFFFATDCLE EMNRWMNRLG
LAAIGYTPDD KVPRPDEDYW SESDQDDVDG SMTLKQEGPP SLCDTYHRTP SVNSSSPFPE
PKHGRHFSSE STHSHSSAED QRGDSIGMGT GTGSTSTHSS GCRSSHRERR SWQDLIETPL
TSAGLHFLQT APGESDYGGL MGTMAGDMGL YGGLGRQGMS PERRRQATLP VRRHHAAERD
RERDGPFPLE RGPYSYSHTH RHSHKQRSQS LPRNRDPMPG RLLHTSIHME ERSEDEEAED
QAADLLPGED VIDLPLSDPL LGVSDLRELR VESRERRISD GRERRVSESC ELEMSDGLEQ
LYRALEQANL TALGDPKPCS RQELRRCFTQ RARDPLLNDR LHRVRVLRST LKAKESELAV
ICALLEDPGL CSQTFREWKQ WHSELYSDIC QLSPGTNGQD DLSPLGAPLM THTHSFIETH
V
//
