ID Q4RTI6_TETNG Unreviewed; 1071 AA.
AC Q4RTI6;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=(spotted green pufferfish) hypothetical protein {ECO:0000313|EMBL:CAG08296.1};
GN ORFNames=GSTENG00029233001 {ECO:0000313|EMBL:CAG08296.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG08296.1};
RN [1] {ECO:0000313|EMBL:CAG08296.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG08296.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG08296.1}.
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DR EMBL; CAAE01014998; CAG08296.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4RTI6; -.
DR KEGG; tng:GSTEN00029233G001; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 5.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45836; SLIT HOMOLOG; 1.
DR PANTHER; PTHR45836:SF9; SLIT HOMOLOG 3 PROTEIN; 1.
DR Pfam; PF00008; EGF; 5.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF01463; LRRCT; 4.
DR Pfam; PF01462; LRRNT; 2.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 6.
DR SMART; SM00369; LRR_TYP; 11.
DR SMART; SM00082; LRRCT; 4.
DR SMART; SM00013; LRRNT; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF52058; L domain-like; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 6.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 6.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 760..795
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 797..836
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 838..874
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 876..914
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 916..952
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 961..997
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 785..794
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 826..835
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 864..873
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 904..913
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 942..951
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 987..996
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1071 AA; 118164 MW; 43A8948A027D03E0 CRC64;
MCAYVRASVK LNPSTKASRA VLAVRGSTLN NNNITLIPLS SFNHMPKLRT LRLHSNNLHC
DCHLSWLSDW LRARRGLAPF TQCMAPAHMR GLNVPDVQKK DFVCNVKMVK TAQWPSKTVK
RVMLLSAGPA LTEPRTCVPQ VAVCPPSCSC NNNIVDCRRK GLTEIPGNLP EAIVEIRLEQ
NLIKSVPAGA FSTYKKLKRI DLSKNQISDI AADAFSGLRS LTSLVLYGNK ITELPKGLFD
GLVSLQLLLL NANKINCLRV NTFQDLQNLN LLSLYDNKLQ SISKGLFAPL RSIKTLHLAQ
NPFMCDCHLK WLADYLFDNP IETSGARCSH PRRLANKRIS QVKGKKFRCT GQEDYRSRLN
GECFQDLVCP EKCRCEGTVV DCSNLKLTRV PPHIPEHTTD LRLNDNEIVV LEAAGIFKKL
PNLKKINLSN NKLRDIREGA FDGASGVLEL LLTGNKLTGL QGRMFRGLNG LKTLNDWLML
SCIFMLSIDS LMASGLSLYH VKGLPVPVIA LLTSNLLSNP YVCDCHLAWL GHWLKKTRVV
SGNPRCQKPA FLKEIPIQDV ATPDFTCDVR PHSRLLPAPP SQISHCLSLR SHTFTSSEGY
LEGNMLTSVP KELAGMKQLS LVDLSNNSIS TLAPFTFSNM TQLATLILSY NQIRCIPVYA
FDGLKALRLL TLHGNDLSTI PEGAFNHLTS LSHLALGANP LYCNCEMRWL SQWVKAGFKE
PGIARCTGPP EMADRLLLTT PLNKFQCKGP TDLSLLSKCA PCLGAPCQNN GTCVSDATGS
YLCMCPYGFK GQNCEIPINA CISLPCSNGG TCHVQPGHED HFSCVCPPGF EGHRCETNPD
DCEDNDCENN STCVDGVNNY TCVCPPNYTG DLCDEVIDPC LHGFDPCQQD SKCVRVGRSY
RCECLPGYVG QQCEQDYNDC LENKCQHGAE CVDAVNGYIC VCKEGFSGLF CENPPPMILL
QTSPCDQSDC QNGAQCLVVA GEPVCRCTPG FYGSKCDKIS TVHFLGRDAF VELPGAKLRP
TAHISLQVAT EKDNGILLYK DDHDPLALEL YQGHIRLIYD FANYPPTTVY R
//
