ID Q4S376_TETNG Unreviewed; 759 AA.
AC Q4S376;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 28-JUN-2023, entry version 87.
DE RecName: Full=Sulfate anion transporter 1 {ECO:0000256|RuleBase:RU362052};
DE AltName: Full=Solute carrier family 26 member 1 {ECO:0000256|RuleBase:RU362052};
DE Flags: Fragment;
GN ORFNames=GSTENG00024764001 {ECO:0000313|EMBL:CAG04906.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG04906.1};
RN [1] {ECO:0000313|EMBL:CAG04906.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG04906.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sodium-independent sulfate anion transporter. Can transport
CC other anions including bicarbonate, thiosulfate and oxalate.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CAG04906.1}.
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DR EMBL; CAAE01014752; CAG04906.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4S376; -.
DR KEGG; tng:GSTEN00024764G001; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR11814:SF31; SULFATE ANION TRANSPORTER 1; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 3.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Anion exchange {ECO:0000256|RuleBase:RU362052};
KW Antiport {ECO:0000256|RuleBase:RU362052};
KW Ion transport {ECO:0000256|RuleBase:RU362052};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 226..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 386..405
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 417..440
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 484..517
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 538..566
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 594..749
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG04906.1"
FT NON_TER 759
FT /evidence="ECO:0000313|EMBL:CAG04906.1"
SQ SEQUENCE 759 AA; 82535 MW; 0A0ABADD883FAFE6 CRC64;
PLLERQSRQR PSAVSALKSK LKSGVSCSAS RVRSTLTGFF PVVRWLPKYK LREYIWGDVM
SGMIVGIILV PQAIAYCLLA GVEPIYGLYT SFYANIIYFL MGTSRHVSVG IFSLMSLMVG
QVVDKELFLA GFDLNEDSPT TASDLFNATL GLNSTSEVHT VELMGVQCGK ACYAISVASA
LTFLAGVYQV NSWILTSPPV RGATSAGFIS ICWLDTRTCA VLQPSVLFLA LPQVLMAVFQ
LGFVSVFLSS PMLDGFATGA SFTILTVQAK YLLGLKIPRH QGYGTVVITW INIFSNIHKT
NLCDLITSAI CISVLVAGKE IQERFKDRLK IPLPTELVVV AGATLASHYG ELNRRYSSSV
SGHIPTGFIP PQVPSFSLMP RVALDAIPLA VISFAFTVSL SEMFAKKNGY TVRPNQEMLA
IGFCNIIPSF FHCFTTSAAL AKTMVKDSTG CQTQVSNMSR SQTVDAPGQF GPNAVLAPPQ
VSSLISALVV LFILLFFAPF FYDLQKCVLA CIIIVSLRGA LRKFKDVPSK WRSSRNDAVV
WLVTMAATAL VSVELGLLVG IVFSMICVIF KIQTPAVSLL GRADGTELYE DVEEYQNLTS
PPGVQVFRFQ APLYYANKDV FLKSLYRAVG VEPFLELTRR KKSQKKKTAN QEKVNGAKSN
GEAAVSLQAE LRFHTIVLDC SAVPFVDSSG LSTLKGLLKE YKDVGVSVLF CGCNASVIDA
MKKAQVFGKN DKDMSSLLFY TVHGAVLHAN ASFTEAQSS
//
