ID Q4SB54_TETNG Unreviewed; 1019 AA.
AC Q4SB54;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Chromosome undetermined SCAF14677, whole genome shotgun sequence {ECO:0000313|EMBL:CAG02128.1};
GN ORFNames=GSTENG00021126001 {ECO:0000313|EMBL:CAG02128.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAG02128.1};
RN [1] {ECO:0000313|EMBL:CAG02128.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAG02128.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the osteocalcin/matrix Gla protein family.
CC {ECO:0000256|ARBA:ARBA00008850}.
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DR EMBL; CAAE01014677; CAG02128.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4SB54; -.
DR KEGG; tng:GSTEN00021126G001; -.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd09575; SAM_DGK-delta; 1.
DR Gene3D; 3.30.60.20; -; 3.
DR Gene3D; 4.10.740.10; Coagulation Factor IX; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR017857; Coagulation_fac-like_Gla_dom.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR037606; DGK-delta_SAM.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR035972; GLA-like_dom_SF.
DR InterPro; IPR000294; GLA_domain.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF30; DIACYLGLYCEROL KINASE DELTA; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF00594; Gla; 1.
DR Pfam; PF07647; SAM_2; 1.
DR PRINTS; PR00001; GLABLOOD.
DR SMART; SM00109; C1; 3.
DR SMART; SM00046; DAGKc; 1.
DR SMART; SM00069; GLA; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 3.
DR SUPFAM; SSF57630; GLA-domain; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50146; DAGK; 1.
DR PROSITE; PS00011; GLA_1; 1.
DR PROSITE; PS50998; GLA_2; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1019
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004243844"
FT DOMAIN 43..89
FT /note="Gla"
FT /evidence="ECO:0000259|PROSITE:PS50998"
FT DOMAIN 152..202
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 263..410
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT DOMAIN 754..854
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 503..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 853..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..547
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1019 AA; 112810 MW; BF800762A0FD8874 CRC64;
MRPTAAVRLL ALLFLSTLAR CTVFLDPSSA ARVLRPSTRG RRANAFALEE LLPGDLEREC
YEETCSQEEA AEIFHTKEKT LEFWFRYVEV TECRHRNGGC WQYCADVPGG VECGAPTDNR
KEMEEWMAAL RSVQNRQNYE STQYSMDHFS GMHNWYACSH ARPTYCNVCR EALSGVTSHG
LSCEVCKFKA HKRCAVRATN NCKWTTLASI GKDIIEDEDG VSMPHQWLEG NLPVSAKCHV
CDKTCGSVLR LQDWRCLWCK AMSGDNQGVK FLRRFKQLLN PAQVFDLMNG GPHLGLRLFQ
KFDTFRILVC GGDGSVGWVL SEIDALTLHK QVRLCRRSRR AAAPARRGAD RQLCVQCQLG
VLPLGTGNDL ARVLGWGSAC DDDTQLPQIL EKLERASTKM LDRWSIMVYE TKFPRQHSVS
TVQQILTYED SVAAHLSKIL TSDQHSVVIS SAKVLCETVK DFVARVGKAY EKNTESSEES
EAMAKKCGVL KEKLDSLLKT LNEESQASSV PHLAPPPTIA EEQEETEGNT SPPPLPHHPP
PPPLPHSCSS RSGASPAAAA IFKPREQLML RANSLKKAIR QIIEHTEKVG KTPCEKLMGK
GSREGTPLLS TKILYPGISV LTSQLRRRNN FWGGLKKTII REVAQCHHSL EQELAHAVNA
SSKAMDLVYA NSKGSGVNQA AGPALGCVCW LFGCRSAFPS ARPPSRPQTL GCGLVLQMVV
NVKVLLRETE LLLAGKMSMG PLTDFSKRSR IHQWGTEEVG AWLDFLCLTE YKDIFTGHDV
RGAELLHLER RDLKVPTPRL LPQWNLHFLS LEPGPSRRLG GAGLTVSLLL QDLGVTKVGH
MKRILQGIRE LNRSSSASNS ARPGDGPVQE GPSSQKAPQW PAVTPGVPNI AKTRQPAASR
RAPRQRPKPC TVCKFKAHKR CAVRATNNCK WTTLASIGKD IIEDEDGVSM PHQWLEGNLP
VSAKCHVCDK TCGSVLRLQD WRCLWCKAMV RPVATVTDAA SVSSCLILTA AKEKQRHSP
//
