ID Q4SKR4_TETNG Unreviewed; 855 AA.
AC Q4SKR4;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Chromosome undetermined SCAF14565, whole genome shotgun sequence {ECO:0000313|EMBL:CAF98768.1};
DE Flags: Fragment;
GN ORFNames=GSTENG00016591001 {ECO:0000313|EMBL:CAF98768.1};
OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon
OS nigroviridis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Tetraodon.
OX NCBI_TaxID=99883 {ECO:0000313|EMBL:CAF98768.1};
RN [1] {ECO:0000313|EMBL:CAF98768.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15496914; DOI=10.1038/nature03025;
RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N.,
RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., Nicaud S.,
RA Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., Dasilva C.,
RA Salanoubat M., Levy M., Boudet N., Castellano S., Anthouard V., Jubin C.,
RA Castelli V., Katinka M., Vacherie B., Biemont C., Skalli Z., Cattolico L.,
RA Poulain J., De Berardinis V., Cruaud C., Duprat S., Brottier P.,
RA Coutanceau J.-P., Gouzy J., Parra G., Lardier G., Chapple C.,
RA McKernan K.J., McEwan P., Bosak S., Kellis M., Volff J.-N., Guigo R.,
RA Zody M.C., Mesirov J., Lindblad-Toh K., Birren B., Nusbaum C., Kahn D.,
RA Robinson-Rechavi M., Laudet V., Schachter V., Quetier F., Saurin W.,
RA Scarpelli C., Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.;
RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals the
RT early vertebrate proto-karyotype.";
RL Nature 431:946-957(2004).
RN [2] {ECO:0000313|EMBL:CAF98768.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope;
RG Whitehead Institute Centre for Genome Research;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CAAE01014565; CAF98768.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4SKR4; -.
DR KEGG; tng:GSTEN00016591G001; -.
DR UniPathway; UPA00143; -.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF177; CULLIN-2; 1.
DR Pfam; PF00888; Cullin; 3.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 3.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT TRANSMEM 623..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 424..728
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAF98768.1"
FT NON_TER 855
FT /evidence="ECO:0000313|EMBL:CAF98768.1"
SQ SEQUENCE 855 AA; 99670 MW; B1C1F0BA1E41BEC1 CRC64;
TMSLKPRVVD FDETWNKLLT TIKAVVMLDY VERATWNDRF SDIYALCVAY PEPLGERLYT
ETKVFLENHV RQLYKKVLDS EEKVLSMYHR YWDEYSKGAD YMDCLYRYLN TQFIKKNKLT
EADLQYGYGG VDMNEPLMEI GELALDTWRK LMIEPLQTVL IRMLLNEIKN DRCGENPNQT
VIHGVINSFV HVEQYKKKCP LKFYQEIFEG LFLTKTGEYY KQEASNLLQE SNCSQYMEKV
LGRLKDEEMR CRKYLHPSSY AKVIHECQQR MVADHLHFLH GECQNIIRQE KRDGQSFDMA
NMYTLLRAVS NGLPHMIQEL QVHIHNEGIR GTSNLSQENM PTLFVESVLE VHSKFVQLIN
TVLNGDQHFM SALDKALTSV VNFREPKSIC KAPELVSLHP HTRTALYTHG FDQVTFRLFV
SVQLAKYCDN LLKKSAKGMT ENEVEDKLTS FITVFKYIDD KDIFQKVIGI IRPCATLRCV
LRVCPFLKTA PNFNWFCFTP QFYARMLAKR LIHGLSLSMD SEEAMINKLK QACGYEFTSK
LHRMYTDMSV SADLNNKFNN FIKTQDTVVD LGISFQIYVL QAGAWPLTHV PSSTFAIPQE
LEKSVQMFEL FYNQHFSGRK LTWLHYLCTG RTLIFFMLIV FFFFLICELE CKNPVFRLRT
APPNLLCSCP TGEVKMNYLT KPYVAMVTTY QMAVLLAFNN SQTVTYKELQ DGTQMNEKEL
QKTIKSLLDV KMLNHDSQKE EIEIESTFSL NMNFTSKRTK FKITTSMQKD TPQEMEQTRS
AVDEDRKMYL QAAIVRIMKA RKVLRHNALI QEVINQSKAR FNPSISMIKK CIEVLIDKQY
IERSQTSADE YSYVA
//
