ID Q4TT46_HUMAN Unreviewed; 113 AA.
AC Q4TT46;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Synapsin III {ECO:0000313|Ensembl:ENSP00000388582.1};
DE Flags: Fragment;
GN Name=SYN3 {ECO:0000313|Ensembl:ENSP00000388582.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000388582.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000388582.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10591208; DOI=10.1038/990031;
RA Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M.,
RA Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C.,
RA Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E.,
RA Bridgeman A.M., Buck D., Burgess J., Burrill W.D., Burton J., Carder C.,
RA Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G.,
RA Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V.,
RA Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M.,
RA Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A.,
RA Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C.,
RA Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E.,
RA Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F.,
RA Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M.,
RA Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A.,
RA Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D.,
RA Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y.,
RA Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S.,
RA Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E.,
RA Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L.,
RA Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L.,
RA Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N.,
RA Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A.,
RA Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L.,
RA Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P.,
RA Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P.,
RA Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q.,
RA Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J.,
RA Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J.,
RA Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D.,
RA Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T.,
RA Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P.,
RA Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K.,
RA Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R.,
RA Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L.,
RA McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J.,
RA Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E.,
RA Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P.,
RA Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y.,
RA Wright H.;
RT "The DNA sequence of human chromosome 22.";
RL Nature 402:489-495(1999).
RN [2] {ECO:0000313|Ensembl:ENSP00000388582.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL021452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF457405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF511444; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z71183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z75744; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z80902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z82181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z82246; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q4TT46; -.
DR SMR; Q4TT46; -.
DR MassIVE; Q4TT46; -.
DR PeptideAtlas; Q4TT46; -.
DR ProteomicsDB; 62256; -.
DR Antibodypedia; 25287; 140 antibodies from 22 providers.
DR Ensembl; ENST00000412575.1; ENSP00000388582.1; ENSG00000185666.16.
DR UCSC; uc062dok.1; human.
DR HGNC; HGNC:11496; SYN3.
DR VEuPathDB; HostDB:ENSG00000185666; -.
DR GeneTree; ENSGT00940000155415; -.
DR OMA; GPHKCIL; -.
DR ChiTaRS; SYN3; human.
DR Proteomes; UP000005640; Chromosome 22.
DR Bgee; ENSG00000185666; Expressed in primordial germ cell in gonad and 119 other cell types or tissues.
DR ExpressionAtlas; Q4TT46; baseline and differential.
DR Gene3D; 3.40.50.20; -; 1.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR019736; Synapsin_P_site.
DR InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR PANTHER; PTHR10841; SYNAPSIN; 1.
DR PANTHER; PTHR10841:SF27; SYNAPSIN-3; 1.
DR Pfam; PF02078; Synapsin; 1.
DR Pfam; PF10581; Synapsin_N; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR PROSITE; PS00415; SYNAPSIN_1; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:Q4TT46,
KW ECO:0007829|PeptideAtlas:Q4TT46};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 89..113
FT /note="Synapsin pre-ATP-grasp"
FT /evidence="ECO:0000259|Pfam:PF02078"
FT REGION 16..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 113
FT /evidence="ECO:0000313|Ensembl:ENSP00000388582.1"
SQ SEQUENCE 113 AA; 12362 MW; BA9EE5B0AAD80771 CRC64;
MNFLRRRLSD SSFMANLPNG YMTDLQRPDS STSSPASPAM ERRHPQPLAA SFSSPGSSLF
SSLSSAMKQA PQATSGLMEP PGPSTPIVQR PRILLVIDDA HTDWSKYFHG KKV
//
