ID Q4U1N9_9NEOP Unreviewed; 345 AA.
AC Q4U1N9;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|ARBA:ARBA00013870};
DE Flags: Fragment;
GN Name=EF-1a {ECO:0000313|EMBL:AAY44117.1};
GN Synonyms=Ef-1a {ECO:0000313|EMBL:ALA63215.1};
OS Anthene emolus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Lycaenidae; Polyommatinae; Anthene.
OX NCBI_TaxID=328895 {ECO:0000313|EMBL:AAY44117.1};
RN [1] {ECO:0000313|EMBL:AAY44117.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16048773; DOI=10.1098/rspb.2005.3124;
RA Wahlberg N., Braby M.F., Brower A.V.Z., de Jong R., Lee M.-M., Nylin S.,
RA Pierce N.E., Sperling F.A.H., Vila R., Warren A.D., Zakharov E.;
RT "Synergistic effects of combining morphological and molecular data in
RT resolving the phylogeny of butterflies and skippers.";
RL Proc. R. Soc. B 272:1577-1586(2005).
RN [2] {ECO:0000313|EMBL:ALA63215.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26265256; DOI=10.1016/j.ympev.2015.08.006;
RA Espeland M., Hall J.P., DeVries P.J., Lees D.C., Cornwall M., Hsu Y.F.,
RA Wu L.W., Campbell D.L., Talavera G., Vila R., Salzman S., Ruehr S.,
RA Lohman D.J., Pierce N.E.;
RT "Ancient Neotropical origin and recent recolonisation: Phylogeny,
RT biogeography and diversification of the Riodinidae (Lepidoptera:
RT Papilionoidea).";
RL Mol. Phylogenet. Evol. 93:296-306(2015).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; DQ018913; AAY44117.1; -; Genomic_DNA.
DR EMBL; KT286211; ALA63215.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4U1N9; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:AAY44117.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000313|EMBL:AAY44117.1}.
FT DOMAIN 1..168
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAY44117.1"
FT NON_TER 345
FT /evidence="ECO:0000313|EMBL:AAY44117.1"
SQ SEQUENCE 345 AA; 37439 MW; CF48DF0991792125 CRC64;
IALWKFETAK YYVTIIDAPG HRDFIKNMIT GTSQADCAVL IVAAGTGEFE AGISKNGQTR
EHALLAFTLG VKQLIVGVNK MDSTEPPYSE SRFEEIKKEV SSYIKKIGYN PAAVAFVPIS
GWHGDNMLEV STKMPWFKGW NVERKEGKAE GKCLIEALDA ILPPARPTDK ALRLPLQDVY
KIGGIGTVPV GRVETGVLKP GTIVVFAPAN ITTEVKSVEM HHEALQEAVP GDNVGFNVKN
VSVKELRRGY VAGDSKNNPP KGAADFTAQV IVLNHPGQIS NGYTPVLDCH TAHIACKFAE
IKEKVDRRSG KSTEDNPKSI KSGDAAIVNL VPSKPLCVES FQEFP
//
