ID Q4U1Q2_9NEOP Unreviewed; 404 AA.
AC Q4U1Q2;
DT 19-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 19-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|ARBA:ARBA00013870, ECO:0000256|RuleBase:RU000325};
DE Flags: Fragment;
GN Name=EF-1a {ECO:0000313|EMBL:AAY44104.1};
OS Urbanus dorantes.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Hesperioidea;
OC Hesperiidae; Eudaminae; Eudamini; Urbanus.
OX NCBI_TaxID=328865 {ECO:0000313|EMBL:AAY44104.1};
RN [1] {ECO:0000313|EMBL:AAY44104.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16048773; DOI=10.1098/rspb.2005.3124;
RA Wahlberg N., Braby M.F., Brower A.V.Z., de Jong R., Lee M.-M., Nylin S.,
RA Pierce N.E., Sperling F.A.H., Vila R., Warren A.D., Zakharov E.;
RT "Synergistic effects of combining morphological and molecular data in
RT resolving the phylogeny of butterflies and skippers.";
RL Proc. R. Soc. B 272:1577-1586(2005).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982, ECO:0000256|RuleBase:RU000325}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249,
CC ECO:0000256|RuleBase:RU000325}.
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DR EMBL; DQ018900; AAY44104.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4U1Q2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAY44104.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000325};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU000325,
KW ECO:0000313|EMBL:AAY44104.1}.
FT DOMAIN 1..223
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAY44104.1"
FT NON_TER 404
FT /evidence="ECO:0000313|EMBL:AAY44104.1"
SQ SEQUENCE 404 AA; 44190 MW; D0630EABC27D6ADC CRC64;
KSTTTGHLIY KCGGIDKRTI EKFEKEAQEM GKGSFKYAWV LDKLKAERER GITIDIALWK
FETAKYYVTI IDAPGHRDFI KNMITGTSQA DCAVLIVAAG TGEFEAGISK NGQTREHALL
AFTLGVKQLI VGVNKMDSTE PPYSESRFEE IKKEVSSYIK KIGYNPAAVA FVPISGWHGD
NMLEPSTKMP WFKGWNVERK KGKAEGKCLI EALDAILPPA RPTDKALRLP LQDVYKIGGI
GTVPVGRVET GILKPGTIVV FAPANITTEV KSVEMHHEAL QEAVPGDNVG FNVKNVSVKE
LRRGYVAGDS KNNPPKGAAD FTAQVIVLNH PGQISNGYTP VLDCHTAHIA CKFAEIKEKV
DRRTGKSTEE NPKSIKSGDA AIVNLVPSKP LCVESFQEFP PLGR
//
