ID Q4U5W2_METIG Unreviewed; 342 AA.
AC Q4U5W2; F6BDC4;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Large ribosomal subunit protein uL10 {ECO:0000256|HAMAP-Rule:MF_00280};
DE AltName: Full=Acidic ribosomal protein P0 homolog {ECO:0000256|HAMAP-Rule:MF_00280};
GN Name=rpl10 {ECO:0000256|HAMAP-Rule:MF_00280};
GN Synonyms=rplP0 {ECO:0000256|HAMAP-Rule:MF_00280};
OS Methanotorris igneus (Methanococcus igneus).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanotorris.
OX NCBI_TaxID=2189 {ECO:0000313|EMBL:AAY33767.1};
RN [1] {ECO:0000313|EMBL:AAY33767.1}
RP NUCLEOTIDE SEQUENCE.
RA Shcherbakov D., Dontsova M., Tribus M., Garber M., Piendl W.;
RT "Mechanisms determining the thermal stability of archaeal ribosomes:
RT analysis of the 'stalk' region.";
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC the interaction of the ribosome with GTP-bound translation factors.
CC {ECO:0000256|HAMAP-Rule:MF_00280}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms part of the ribosomal
CC stalk which helps the ribosome interact with GTP-bound translation
CC factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10
CC forms an elongated spine to which the L12 dimers bind in a sequential
CC fashion. {ECO:0000256|HAMAP-Rule:MF_00280}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000256|ARBA:ARBA00008889, ECO:0000256|HAMAP-Rule:MF_00280}.
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DR EMBL; DQ009621; AAY33767.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4U5W2; -.
DR GeneID; 10643788; -.
DR OMA; DMNPFKL; -.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd05795; Ribosomal_P0_L10e; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR Gene3D; 6.10.140.760; -; 1.
DR HAMAP; MF_00280; Ribosomal_L10_arch; 1.
DR InterPro; IPR001790; Ribosomal_uL10.
DR InterPro; IPR040637; Ribosomal_uL10-like_insert.
DR InterPro; IPR043164; Ribosomal_uL10-like_insert_sf.
DR InterPro; IPR043141; Ribosomal_uL10-like_sf.
DR InterPro; IPR022909; Ribosomal_uL10_arc.
DR PANTHER; PTHR45699; 60S ACIDIC RIBOSOMAL PROTEIN P0; 1.
DR PANTHER; PTHR45699:SF3; 60S ACIDIC RIBOSOMAL PROTEIN P0; 1.
DR Pfam; PF00428; Ribosomal_60s; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; Ribosomal protein L10-like; 1.
PE 3: Inferred from homology;
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_00280};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_00280}; RNA-binding {ECO:0000256|HAMAP-Rule:MF_00280};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00280}.
FT DOMAIN 119..188
FT /note="Large ribosomal subunit protein uL10-like insertion"
FT /evidence="ECO:0000259|Pfam:PF17777"
FT REGION 303..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 36901 MW; 8E113F19E99A359D CRC64;
MTSAVATQRK IAPWKIEEVK TLKELLKSKP VVAIVDMMEV PARQLQEIRD KIRGKMILRM
SRNSLIIRAI KEVAEETNNP EFAKLADYVE KGAAILVTDM NPFKLFKELE ASKTPAPIKG
GAIAPCDIKV QKGSTGMPPG PFLGELKSVG IPAAIEKGKI VIKEDKVVVK AGEVVSHKLA
TILSTLGIKP IKVGLNLLAA YEDGIIYTPD VLKIDEEEFI SKIQNAYMHA VNLSVNAAIP
TKATIEMLIQ KAFLNARAVS VESAFLTDKT ASDIIGKAYA QMLALAGKLS DDALDDDLRE
RLSASASAAA PAPAAEEKKE EEKKEEKKDD TATAAAGLAL LF
//
