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Database: UniProt
Entry: Q4UJN4
LinkDB: Q4UJN4
Original site: Q4UJN4 
ID   RNPH_RICFE              Reviewed;         239 AA.
AC   Q4UJN4;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   14-MAY-2014, entry version 48.
DE   RecName: Full=Ribonuclease PH;
DE            Short=RNase PH;
DE            EC=2.7.7.56;
DE   AltName: Full=tRNA nucleotidyltransferase;
GN   Name=rph; OrderedLocusNames=RF_0403;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- FUNCTION: Phosphorolytic exoribonuclease that removes nucleotide
CC       residues following the -CCA terminus of tRNA and adds nucleotides
CC       to the ends of RNA molecules by using nucleoside diphosphates as
CC       substrates (By similarity).
CC   -!- CATALYTIC ACTIVITY: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside
CC       diphosphate.
CC   -!- SIMILARITY: Belongs to the RNase PH family.
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DR   EMBL; CP000053; AAY61254.1; -; Genomic_DNA.
DR   RefSeq; YP_246419.1; NC_007109.1.
DR   ProteinModelPortal; Q4UJN4; -.
DR   SMR; Q4UJN4; 2-236.
DR   STRING; 315456.RF_0403; -.
DR   EnsemblBacteria; AAY61254; AAY61254; RF_0403.
DR   GeneID; 3400280; -.
DR   KEGG; rfe:RF_0403; -.
DR   PATRIC; 17891280; VBIRicFel64634_0474.
DR   eggNOG; COG0689; -.
DR   HOGENOM; HOG000229516; -.
DR   KO; K00989; -.
DR   OMA; PLKQMIA; -.
DR   OrthoDB; EOG6CZQQP; -.
DR   BioCyc; RFEL315456:GKEK-416-MONOMER; -.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0009022; F:tRNA nucleotidyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004549; F:tRNA-specific ribonuclease activity; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.230.70; -; 1.
DR   HAMAP; MF_00564; RNase_PH; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR002381; RNase_PH_bac-type.
DR   InterPro; IPR018336; RNase_PH_CS.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55666; SSF55666; 1.
DR   TIGRFAMs; TIGR01966; RNasePH; 1.
DR   PROSITE; PS01277; RIBONUCLEASE_PH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Nucleotidyltransferase; Transferase;
KW   tRNA processing.
FT   CHAIN         1    239       Ribonuclease PH.
FT                                /FTId=PRO_0000277945.
SQ   SEQUENCE   239 AA;  25978 MW;  ABF5229C33760D9C CRC64;
     MRQSGRKSNQ LRPISLELSP LINAEGSCLI KIGNTHVMCS ATCETTVPPF LRGQNQGWVT
     AEYGMLPGST SQRIKREAAQ GKQGGRTQEI QRLIGRNMRC VIDLKKLGER QIIIDCDVIN
     ADGGTRTAAI TGSYVALHLA IRSLMKKRIL KVNPLISQIA AVSCGIYKGE AILDLDYLED
     SDAEVDSNFV FAGNGNLIEV QGTAEKEPFS EEQFIAMLKL AKGGAAELFK LQNQVLLGA
//
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