ID Q4UK71_RICFE Unreviewed; 1594 AA.
AC Q4UK71;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=NAD-specific glutamate dehydrogenase {ECO:0000313|EMBL:AAY62064.1};
GN OrderedLocusNames=RF_1213 {ECO:0000313|EMBL:AAY62064.1};
OS Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX NCBI_TaxID=315456 {ECO:0000313|EMBL:AAY62064.1, ECO:0000313|Proteomes:UP000008548};
RN [1] {ECO:0000313|EMBL:AAY62064.1, ECO:0000313|Proteomes:UP000008548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC VR-1525 / URRWXCal2 {ECO:0000313|Proteomes:UP000008548};
RX PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.E.,
RA Parinello H., Claverie J.M., Raoult D.;
RT "The genome sequence of Rickettsia felis identifies the first putative
RT conjugative plasmid in an obligate intracellular parasite.";
RL PLoS Biol. 3:1-12(2005).
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DR EMBL; CP000053; AAY62064.1; -; Genomic_DNA.
DR STRING; 315456.RF_1213; -.
DR KEGG; rfe:RF_1213; -.
DR eggNOG; COG2902; Bacteria.
DR HOGENOM; CLU_003404_1_1_5; -.
DR Proteomes; UP000008548; Chromosome.
DR GO; GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR048381; GDH_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR028971; NAD-GDH_cat.
DR InterPro; IPR049062; NAD_Glu_DH_ACT2.
DR InterPro; IPR049064; NAD_Glu_DH_ACT3.
DR InterPro; IPR007780; NAD_Glu_DH_bac.
DR InterPro; IPR049059; NAD_Glu_DH_HM1.
DR InterPro; IPR049058; NAD_Glu_DH_HM2.
DR InterPro; IPR049056; NAD_Glu_DH_HM3.
DR InterPro; IPR024727; NAD_Glu_DH_N_ACT1.
DR PANTHER; PTHR43403; NAD-SPECIFIC GLUTAMATE DEHYDROGENASE; 1.
DR PANTHER; PTHR43403:SF1; NAD-SPECIFIC GLUTAMATE DEHYDROGENASE; 1.
DR Pfam; PF05088; Bac_GDH_CD; 1.
DR Pfam; PF21075; GDH_ACT1; 1.
DR Pfam; PF21076; GDH_ACT2; 1.
DR Pfam; PF21077; GDH_ACT3; 1.
DR Pfam; PF21074; GDH_C; 1.
DR Pfam; PF21073; GDH_HM1; 1.
DR Pfam; PF21079; GDH_HM2; 1.
DR Pfam; PF21078; GDH_HM3; 1.
DR PIRSF; PIRSF036761; GDH_Mll4104; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 51..174
FT /note="NAD-glutamate dehydrogenase N-terminal ACT1"
FT /evidence="ECO:0000259|Pfam:PF21075"
FT DOMAIN 404..492
FT /note="NAD-glutamate dehydrogenase ACT2"
FT /evidence="ECO:0000259|Pfam:PF21076"
FT DOMAIN 557..613
FT /note="NAD-glutamate dehydrogenase ACT3"
FT /evidence="ECO:0000259|Pfam:PF21077"
FT DOMAIN 720..1209
FT /note="NAD-glutamate dehydrogenase catalytic"
FT /evidence="ECO:0000259|Pfam:PF05088"
FT DOMAIN 1255..1585
FT /note="NAD-specific glutamate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21074"
SQ SEQUENCE 1594 AA; 182489 MW; 25EBE2F9F6DC90A6 CRC64;
MIAYNIILEK IMPPKTTSLN FSRLNCQIPN YKTKILELSK ERESSSIYID FVQKFLNYIP
IDYDFENREK LFQNFADEAF KFFKQRVERA RKIAITKTVI ENDPAINVLI LLDNKPHIVD
FIICLLKNMN LQTKFLLHPV INCVRNSKGE LEKILENSVS DEKSESILHL TILGNFDDKT
TTFLTEAINE RLEELEQSYS HLPQLLTKLQ GLSKNIIDND KLNFEEAKEF LNWLQNDNLV
LLGTLDFEVK SIKLSNEIGA AKIWQEVKDE IDDIIKCSAN PLYQNQLIIL GKINSASLIH
SDNLIDYILV KKFSSSGEYI SGSIIFGIYN SNMYYHSISD IPILRQKFNF VIEKAGFALS
GYNADKLRIL MESLPREALI QIDQGDLYCM CLHMLSSMMS KKLKLFIQYD WSSSFLNIII
FLPRERLTAE IHNMIDCYLA EKFGSKILSN YITEVVGNFS YLFVTLEAQG EHKINFEAEI
IQQDLDRIST RWSEDFYFKL SKKFGEYQAG INLKLFDNVF PADYRQKFSP EIALVDIEYL
TEASKSQECM FNLVSVNETE FYLKIYSPKV KLALSNILPP IENLGFKAID EQTFAIKEAL
EIKESWIYNF ILTSIIPVKG NITELKINVE EALDQMALGM LANDSLSKLI VLAGFNWKQV
KLVKALTRYL HQTGFSYGKG YVQLTLLKHP EYTKMLVNLF DIKFNPKHPD NNCGVIQDKL
NNYLVTVEMS SEDKVLRSML GIINAITRTN YYQPHKHVFS FKFDSSKVPG LPKPVPFAEA
FVYSKDFEAV HLRGGPVSRG GLRWSDRAED YRLEVLGLMK AQMTKNSVIV PVGSKGGFYV
HFTEEGLTRD EYMEKVVECY KNFLRGLLDI TDNIVDGKVV HPKDVIIYDK EDPYLVVAAD
KGTASFSDYA NSVSREYNYW LDDAFASGGS AGYDHKKMAI TSKGAWISVT NHFKTLGLDV
QIDPITVVGI GDMSGDVFGN GMLRSEAIKL VAAFNHKHIF IDPTPDPVSS FNERLRLFNL
KGSNWCDYDS KLISKGGKVF ERSSKLIKLS PEIKKLLDIN DNELSPEELI KAILKADVDL
LWNGGIGTYI KAKTENNLEI GDKANDNLRC NGEEIRAKVI AEGGNVGVSQ RGRVEYAKKG
GRINADFIDN SAGVDCSDHE VNIKIALSSA VTSGKITLEE RNKLLNDMTK QVEELVLLDN
YKQTEAITIM QLSPTLTVNI LSQFIDILEE EKVLERENEF LPSAEELNRR AISGEVLTRP
ELCVLLSYSK RSAYHELLNS TFSHDKYFDS YLIDYFPEMM QKKFRNEILS HPLKHEIIKT
VTINKIINQL GGPLISIVKR EIGSPLCDII RSYTIICEIF DLDDIWETIS KLPTNIDYNV
KIDMFTEITK LMRRGISWFI KNLKHPINIS ETIEEFRVPA QNLRKTVGTL LVGETKIRFE
EKLNYYTTSG VEESFAATIA TFDNLISVFD TIYVTKQTSG NNKEIAKAYF AISDMFSLDW
LRKACDKQLN DSFWRRLGIQ SLKDDLYDKQ RRLLIKIINK SKTTIDLDLW IDNNNNLVRN
FLDFIKEIKS QETIDLNIII LANKKFEIFL QKLE
//
