ID Q4VDE6_CRYGA Unreviewed; 405 AA.
AC Q4VDE6; Q4VDE7; Q4VDF0;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 2.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Sexual development regulator {ECO:0000313|EMBL:AAY42412.2};
GN Name=SXI1alpha {ECO:0000313|EMBL:AAY42412.2};
OS Cryptococcus gattii (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=552467 {ECO:0000313|EMBL:AAY42412.2};
RN [1] {ECO:0000313|EMBL:AAY42412.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JH3713 {ECO:0000313|EMBL:AAY42408.1}, JH3727
RC {ECO:0000313|EMBL:AAY42411.2}, and JH3739
RC {ECO:0000313|EMBL:AAY42412.2};
RX PubMed=16087746; DOI=10.1128/EC.4.8.1410-1419.2005;
RA Campbell L.T., Fraser J.A., Nichols C.B., Dietrich F.S., Carter D.,
RA Heitman J.;
RT "Clinical and environmental isolates of Cryptococcus gattii from Australia
RT that retain sexual fecundity.";
RL Eukaryot. Cell 4:1410-1419(2005).
RN [2] {ECO:0000313|EMBL:AAY42412.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JH3713 {ECO:0000313|EMBL:AAY42408.1}, JH3727
RC {ECO:0000313|EMBL:AAY42411.2}, and JH3739
RC {ECO:0000313|EMBL:AAY42412.2};
RX PubMed=16222245; DOI=10.1038/nature04220;
RA Fraser J.A., Giles S.S., Wenink E.C., Geunes-Boyer S.G., Wright J.R.,
RA Diezmann S., Allen A., Stajich J.E., Dietrich F.S., Perfect J.R.,
RA Heitman J.;
RT "Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii
RT outbreak.";
RL Nature 437:1360-1364(2005).
RN [3] {ECO:0000313|EMBL:AAY42412.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JH3727 {ECO:0000313|EMBL:AAY42411.2}, and JH3739
RC {ECO:0000313|EMBL:AAY42412.2};
RA Fraser J.A., Campbell L.T., Nichols C.B., Dietrich F.S., Carter D.,
RA Heitman J.;
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AEC22314.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=XH91 {ECO:0000313|EMBL:AEC22314.1};
RA Feng X., Yao Z.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TALE/M-ATYP homeobox family.
CC {ECO:0000256|ARBA:ARBA00005800}.
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DR EMBL; AY973646; AAY42408.1; -; Genomic_DNA.
DR EMBL; AY973649; AAY42411.2; -; Genomic_DNA.
DR EMBL; AY973650; AAY42412.2; -; Genomic_DNA.
DR EMBL; HM132027; AEC22314.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4VDE6; -.
DR VEuPathDB; FungiDB:CNBG_5880; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
PE 3: Inferred from homology;
KW Homeobox {ECO:0000256|ARBA:ARBA00023155};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 163..202
FT /note="Homeobox KN"
FT /evidence="ECO:0000259|Pfam:PF05920"
FT REGION 332..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45217 MW; AA7DE8D415A88968 CRC64;
MLSTCDTSSQ SIRKSLQDDL VDFQETFAKI LGKRKIDDNE NVARKCRNLV TAVKWSSSRH
LLDENTVSLA YAVAHNVKVI GSSALQLERG RENAVGDAML RIESLLLDQG RRRKCHQRDY
EPQPKRCCCG SSSESYSTWP ESNLHISPKP SESAPDHTIV RLWFLNNLAY PYPTAQQKES
LAKHARMQRS KVDSDLTNYR RRAGWTDIMN VWCGGDRNAM KKLMEKVERG KEQRKEILDA
VQGCKDYLTM KENNRVGDWV KEITRNSDSK YRFTGILPNV SVASPCSTNQ CSTARSFSGS
SALSSMSSCS EVSEASAIIS IPSKKRYTRD ESISPFKRTR NQTAEVSGSY EPWSIADLQP
MPPSPGAAEE NTANDSIVPA TCLVNASPLS LSSPGETRTK PRLAY
//
