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Database: UniProt
Entry: Q4WC90_ASPFU
LinkDB: Q4WC90_ASPFU
Original site: Q4WC90_ASPFU 
ID   Q4WC90_ASPFU            Unreviewed;       139 AA.
AC   Q4WC90;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   24-JAN-2024, entry version 96.
DE   RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU369086};
GN   ORFNames=AFUA_8G05300 {ECO:0000313|EMBL:EAL85294.1};
OS   Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS   Af293) (Neosartorya fumigata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL85294.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL85294.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: DNA-dependent RNA polymerase which catalyzes the
CC       transcription of DNA into RNA using the four ribonucleoside
CC       triphosphates as substrates. {ECO:0000256|RuleBase:RU369086}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369086}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL85294.1}.
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DR   EMBL; AAHF01000013; EAL85294.1; -; Genomic_DNA.
DR   RefSeq; XP_747332.1; XM_742239.1.
DR   AlphaFoldDB; Q4WC90; -.
DR   STRING; 330879.Q4WC90; -.
DR   EnsemblFungi; EAL85294; EAL85294; AFUA_8G05300.
DR   GeneID; 3504746; -.
DR   KEGG; afm:AFUA_8G05300; -.
DR   eggNOG; KOG3298; Eukaryota.
DR   HOGENOM; CLU_1844637_0_0_1; -.
DR   InParanoid; Q4WC90; -.
DR   OMA; EHEILMH; -.
DR   OrthoDB; 646189at2759; -.
DR   Proteomes; UP000002530; Chromosome 8.
DR   GO; GO:0000932; C:P-body; IBA:GO_Central.
DR   GO; GO:0005665; C:RNA polymerase II, core complex; IBA:GO_Central.
DR   GO; GO:1990328; C:RPB4-RPB7 complex; IEA:EnsemblFungi.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:EnsemblFungi.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR   GO; GO:0031369; F:translation initiation factor binding; IBA:GO_Central.
DR   GO; GO:0000291; P:nuclear-transcribed mRNA catabolic process, exonucleolytic; IBA:GO_Central.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IBA:GO_Central.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IBA:GO_Central.
DR   GO; GO:0010590; P:regulation of septum digestion after cytokinesis; IEA:EnsemblFungi.
DR   GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:EnsemblFungi.
DR   GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IBA:GO_Central.
DR   CDD; cd04329; RNAP_II_Rpb7_N; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.30.1490.120; RNA polymerase Rpb7-like, N-terminal domain; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR   InterPro; IPR045113; Rpb7-like.
DR   InterPro; IPR005576; Rpb7-like_N.
DR   PANTHER; PTHR12709:SF4; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7; 1.
DR   PANTHER; PTHR12709; DNA-DIRECTED RNA POLYMERASE II, III; 1.
DR   Pfam; PF03876; SHS2_Rpb7-N; 1.
DR   SUPFAM; SSF88798; N-terminal, heterodimerisation domain of RBP7 (RpoE); 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE   4: Predicted;
KW   DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW   ECO:0000256|RuleBase:RU369086};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:EAL85294.1};
KW   Nucleus {ECO:0000256|RuleBase:RU369086};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU369086}; Transferase {ECO:0000313|EMBL:EAL85294.1}.
FT   DOMAIN          9..63
FT                   /note="RNA polymerase Rpb7-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03876"
SQ   SEQUENCE   139 AA;  15586 MW;  1E7DD15BB88C9415 CRC64;
     MFFLKEETKV ISLHPSYFGP NMREYLINRL NEEEEGRCTG DHFVICVMDM VDIGEGRVLP
     GSGQAEYTIK YRAIIWKPFR GETVDAIVTS VKPTGIFTLA GPLSVFIARK YLLSTRIMPT
     RSSKRGPVYG SKSSVSSLT
//
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