ID   Q4WKP8_ASPFU            Unreviewed;      1165 AA.
AC   Q4WKP8;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   01-MAY-2013, entry version 62.
DE   SubName: Full=Protein kinase and ribonuclease Ire1, putative;
DE            EC=2.7.1.-;
GN   ORFNames=AFUA_1G01720;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae;
OC   mitosporic Trichocomaceae; Aspergillus.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S.,
RA   Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W.,
RA   Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S.,
RA   Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R.,
RA   Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A.,
RA   Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J.,
RA   Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J.,
RA   Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S.,
RA   Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A.,
RA   Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M.,
RA   Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I.,
RA   Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M.,
RA   Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S.,
RA   Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J.,
RA   White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K.,
RA   Machida M., Hall N., Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data.
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DR   EMBL; AAHF01000007; EAL87884.1; -; Genomic_DNA.
DR   RefSeq; XP_749922.1; XM_744829.1.
DR   ProteinModelPortal; Q4WKP8; -.
DR   STRING; 5085.CADAFUAP00009158; -.
DR   EnsemblFungi; CADAFUAT00009158; CADAFUAP00009158; CADAFUAG00009158.
DR   GeneID; 3507278; -.
DR   KEGG; afm:AFUA_1G01720; -.
DR   HOGENOM; HOG000213215; -.
DR   KO; K08852; -.
DR   OMA; NILWFVE; -.
DR   OrthoDB; EOG4DBXNV; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   InterPro; IPR010513; KEN_dom.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR011047; Quinonprotein_ADH-like_supfam.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF06479; Ribonuc_2-5A; 1.
DR   SMART; SM00564; PQQ; 2.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   SUPFAM; SSF50998; Quin_alc_DH_like; 1.
DR   PROSITE; PS51392; KEN; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Complete proteome; Kinase; Reference proteome; Transferase.
SQ   SEQUENCE   1165 AA;  130049 MW;  4B8DD0D89D9AFB94 CRC64;
     MRWRLPGART TLPASVALLL LPILVAPQQL QEHDDLPSTL SVPLSPTQRS FDHHPLPTIN
     VKSNDASALA TMALAGPGRA VRARPAQASS SSAGLAPQLH ARSLQDWEVE DFVLLATVDG
     SIHARDRRTG AARWALEVPS SPMVESIYHR ANRSSFDRAQ PEDDFLWIVE PSQDGNLYIY
     SPGPDAGLQK LGLTVKELVE QTPYSGTDPA VTYTARKETT LYTVDARTGN ILQVFSSRGP
     ITSGHGCRKV DGFDLEAEEC DTPSGTLVLG RVEYAVAIQN TETGDPICTL KYSEWTANNR
     DMDLQSQYFR TMDQSHIYSM HDGVVLGFDH SRMDRPRYTQ RFSSPVVRVF DVARPINVES
     PEAATPLVLL SQPLQPPDPD YGSLDDRDAR VFVDCTSAGG WFAMSEETYP LVTGRAKMAQ
     CYEKDYLRHG QPLTSLPTSQ QRDALAGVHS LNGPRVVRNT PSISGPSPLE LANDTPRELM
     RSPSELALPP ALRHSTIIRK GWDNAVDIFV TILLLFFGAF IYFNSHNIQE LAKQKLDVKN
     IIASYAQPPL STPSTPVVES THFKRDSSPS RPISNLTVEV TVPEEQQEGD ATPKPKRDRS
     AVGPDSTPRV KIREPSRGPD SDDDVEELDQ AASPEKPKKK ARRGRRGGKN HRRGKKPDSE
     GESKDQADRV VDQVNNLQPQ SRLEPDLQLV RTVSNDIIEM DGVLQIGRLR VFSDVVLGHG
     SHGTVVYRGS FDGRDVAVKR MLVEFYDIAS HEVGLLQESD DHNNVIRYFC REQAAGFLYI
     ALELCPASLQ DLIERPGDYP QLVQGGLDMP DILRQIIAGV RYLHSLKIVH RDLKPQNILV
     AMPRGRTGSR SLRLLISDFG LCKKLDDNQS SFRATTAHAA GTSGWRAPEL LVDDDNRSAI
     QGGESQHTES SEPAVVDPQT NRRATRAIDI FSLGCVFYYV LTRGSHPFDK NGKFMREANI
     VKGNFNLDEL QRLGDYAFEA DDLIRSMLSL DPRKRLAPLC SSLAFRLFTD LFPRPDASAV
     LMHPFFWNPS DRLSFLCDVS DHFEFEPRDP PSDALLCLES VACRVMGPEM DFLRLLPKDF
     KDNLGKQRKY TGSKMLDLLR ALRNKRNHYN DMPAHLKAHI GGLPEGYLNF WTVRFPSLLM
     SCHSVIVELR LTKIDRFKRY FTPVE
//