ID Q4WKY4_ASPFU Unreviewed; 632 AA.
AC Q4WKY4;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Aminoglycoside phosphotransferase domain-containing protein {ECO:0000259|Pfam:PF01636};
GN ORFNames=AFUA_1G00840 {ECO:0000313|EMBL:EAL87798.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL87798.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL87798.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC {ECO:0000256|ARBA:ARBA00006219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL87798.1}.
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DR EMBL; AAHF01000007; EAL87798.1; -; Genomic_DNA.
DR RefSeq; XP_749836.1; XM_744743.1.
DR AlphaFoldDB; Q4WKY4; -.
DR EnsemblFungi; EAL87798; EAL87798; AFUA_1G00840.
DR GeneID; 3507534; -.
DR KEGG; afm:AFUA_1G00840; -.
DR VEuPathDB; FungiDB:Afu1g00840; -.
DR HOGENOM; CLU_432740_0_0_1; -.
DR InParanoid; Q4WKY4; -.
DR OMA; IIAWSAD; -.
DR OrthoDB; 2282524at2759; -.
DR Proteomes; UP000002530; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR21310:SF59; AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR21310; AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 168..251
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 632 AA; 73196 MW; 3A43FF2951B7BF29 CRC64;
MEKFGRRARS REAEKLAVRY RKFNLPALLD AAVNVTGLDD AQCESLSLLN PRTANCLTIG
IKVLKCVEGQ YNKALVLTMS TGQEIVARLP NPNAGPTFYT TASEVATRQF SDLESRQPRP
SFALVPGQNR GLPKFAIGPL THPKYWQGKR ALMELDRGPS IGKNEIQWAE EHARPRMNFQ
RSVEEPETPG DYISMLQRYN KLVPFLVPPS LCSEQTNTVS HPDLHLDNIF VDPQTNHITS
IIDWQHVSAS PIFLQRPYPQ MLELSQNAQA ECQVIEKQLL EFYFERLKNV DPFRWRMLSE
PLHFIKAEII SLVPCCWDRE DLFSLRNAMI TALAHWNEIS GGGIKRPIEF TDKELEQHQN
EMELVEGVSM ILHQLQEDGL ISLGGMVSPE RYEDARKWNN YFKQEFINLA EDEKQRELHA
KKLAETLHKI SNSRGRITSC REKILSTDPD LDPENWFRCW ESKSGDKLSS KQAIRLAALI
KRWSRRTGED SQTLKDWISN PSTFWGMDPF RTPFEFVRHC LELAEKTEGK EPIRRRVTLI
VLYDIISEEI SRLRRQSNQL RHQKYLTSAV KNIVAKAYHS QNASERTKLH TRLTYLQRYG
EKWSRLERRE IVLAPLDNAR DKLVTTHILL NR
//
