ID Q4WL77_ASPFU Unreviewed; 461 AA.
AC Q4WL77;
DT 05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2005, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=Monooxygenase, putative {ECO:0000313|EMBL:EAL89287.1};
DE EC=1.14.13.1 {ECO:0000313|EMBL:EAL89287.1};
GN ORFNames=AFUA_6G14510 {ECO:0000313|EMBL:EAL89287.1};
OS Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS Af293) (Neosartorya fumigata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL89287.1, ECO:0000313|Proteomes:UP000002530};
RN [1] {ECO:0000313|EMBL:EAL89287.1, ECO:0000313|Proteomes:UP000002530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC {ECO:0000313|Proteomes:UP000002530};
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL89287.1}.
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DR EMBL; AAHF01000006; EAL89287.1; -; Genomic_DNA.
DR RefSeq; XP_751325.1; XM_746232.1.
DR AlphaFoldDB; Q4WL77; -.
DR STRING; 330879.Q4WL77; -.
DR EnsemblFungi; EAL89287; EAL89287; AFUA_6G14510.
DR GeneID; 3508642; -.
DR KEGG; afm:AFUA_6G14510; -.
DR VEuPathDB; FungiDB:Afu6g14510; -.
DR eggNOG; KOG2614; Eukaryota.
DR HOGENOM; CLU_009665_19_5_1; -.
DR InParanoid; Q4WL77; -.
DR OMA; PPTHESM; -.
DR OrthoDB; 5491711at2759; -.
DR Proteomes; UP000002530; Chromosome 6.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0018658; F:salicylate 1-monooxygenase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR PANTHER; PTHR13789:SF309; PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:EAL89287.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EAL89287.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT DOMAIN 4..377
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 461 AA; 51062 MW; F074EEF03050C903 CRC64;
MPCRILIVGG GIAGLTASIA LAKELTKVEP DLDMAIYESR DEHSMGEGGA ISLTPVAQHH
LDQLGVLPEL SRMGDGAGIE VDEINLYSLR SGRSLGPLRF ADETGRGYRG YKSRRVRRSA
LFRAMLAVAR RYAQISVEFD KKLSSTTMDG NTVTLAFNDG TTTTGDLLLG CDGVHSAVRT
QLVDPGNHSE YTGIAFIQSL APAERVSLPS HLNQSAIHLT KQGSLLASYC DPSHQTLFVA
AIMRVNEHII ERYRALASTG TNTAALTSAQ MALRYQVRSK FGTSAFPWIR EWIDKTHDWE
LYPIYQVRQR GKWHVGRALL LGDAAHAMPP REESAAYAIE DAVIFAQIFA RRRGRPLHHI
FQEYENARRE LVDKAFDTTR RLWQSDLDKG LFPGNFRDCM SSTQLPPNRL VMDKADAPMG
EPIFPPPTHE SMSDLSVSTL TSELEAALDA DERRTKVPLS L
//
