ID   Q4WPJ3_ASPFU            Unreviewed;      1447 AA.
AC   Q4WPJ3;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   24-JAN-2024, entry version 74.
DE   SubName: Full=NACHT domain protein {ECO:0000313|EMBL:EAL89841.1};
GN   ORFNames=AFUA_4G09460 {ECO:0000313|EMBL:EAL89841.1};
OS   Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS   Af293) (Neosartorya fumigata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL89841.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL89841.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL89841.1}.
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DR   EMBL; AAHF01000005; EAL89841.1; -; Genomic_DNA.
DR   RefSeq; XP_751879.1; XM_746786.1.
DR   EnsemblFungi; EAL89841; EAL89841; AFUA_4G09460.
DR   GeneID; 3509129; -.
DR   KEGG; afm:AFUA_4G09460; -.
DR   VEuPathDB; FungiDB:Afu4g09460; -.
DR   eggNOG; ENOG502QRJZ; Eukaryota.
DR   HOGENOM; CLU_253650_0_0_1; -.
DR   InParanoid; Q4WPJ3; -.
DR   OMA; SICHWYF; -.
DR   OrthoDB; 1750098at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR031350; Goodbye_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR10039; AMELOGENIN; 1.
DR   PANTHER; PTHR10039:SF14; NACHT AND TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G06670); 1.
DR   Pfam; PF17109; Goodbye; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   DOMAIN          17..137
FT                   /note="Fungal STAND N-terminal Goodbye"
FT                   /evidence="ECO:0000259|Pfam:PF17109"
SQ   SEQUENCE   1447 AA;  163818 MW;  BEA269CA93785E54 CRC64;
     MTRTTSDLLD DRLSTLWQSA CDDYAKETGI ALTDGDFPKI HGPEDLSRHL DAERDHFEDF
     RMKKRPLLHA MQIILAPFEH WGDLLAGVAS AAFPPASSIM GAMMLLVRGA RRVSESFDML
     MDLFHKLGHF ALRLDSYKGV SLSEGMKTII VQVLVNFLRV CAASQKLLRR GSLRARLTKW
     TKNVLVEDTS IRSLLDELEE LTSQEHKMVS AHALDLTHQA LRSTAELLER DDNRNERDRL
     DKVKKALDPV SASGRVFSSL NENRIPGSGS WIEDRIRSWW QSPDPLLWIH GGPGVGKSYL
     ASKIISDLAT ADSSAPSTPP IVASFFFKNN DVDLRSFNKA LRTLAWQVVV QRSRFAAHAE
     DFCLKEDPAN SYVVWRKLLL DFFVKSPPDA GTCFVIDGID EADPEEQEIL FRLLESTYAT
     EDQTGPSAPI RVVLLGRDSV RGILEEHSLG GIPEIEITNN QNQDDLHRYV SQKLQKTKLF
     RGYPDFLDEV VQDICGQAEG LWEWANLVIK SVLRCRSKEQ IRRVVRTMPR GISAMLHAEL
     QRLARELSAS DAMSPELSDG EGSSGDTTTQ IQQLNLLLSF VAMAQKPLTV DQLDLILEVI
     LEEEVLNLED DLRTAYSSLF SLRPALGEGD KGEDDDDDDE VEKDTVIVTL RHSSFYEFFS
     TSVEAGPIQV DPDRAEASFV FVLLYALQRK YAPKSERMLG LISRYAQKFL PLHLERANPE
     KADRREGIAK QLAALLTEEP VFNPQHWLIE QYDVVYVTTY DQYMCSRATD IACYWWNTQK
     RDTANQRAEL VLNWLSPDTK QLLQDCARSS TVASDACPFT VLFSRMAESF SRLWLAPKDI
     EEKDGLPEGL STFLFVYAQM AGTEFPTAEG ELGGVVRIAL RTAEIMQVAE MQRLEKTPVW
     HARVAQALLL HGNYRTALEQ FQICLDDHQR NPVLSKQALF AIHRDMARAC TETGRYREAV
     EHSDLAESLR DASWDSSWQD PIGRLLNAAQ MKHLAKMTDE AVATADEAWE TYRGQKEDYR
     DRYTLHSFFS VFLELHQTHR VQDVLDLAAS HPQEFQFTER IGLVEFLAST LTWTRRLVYR
     VLHHTRTRGD GKLIDLVASA VARAEASEGE LTDDLAAAKY FIASLMVENG RFSAGIQAWY
     QLAALDHPRG DRERAQARSL SRLAAVCLCN PEIPLCDEPP LRLDEKAEYS DICLVISSWL
     RYHGDLANAR TALRGRVKKS IELLSDDDPS NDDDAFLSLF QTLLTAADSD EDLSGALYCT
     KAWYKDCLRE AKSDHRMSEG GVAKSLNQVH LVADETQVPD DGVSERRISY TIDYFAECSN
     CKCEMKSICH WYFCLCCPFM MLCQWCYHEI QSALSQDGTS HPQGICDPQH EFYYTGGPLR
     AVERVPEGMT VLDGLDGTKR TAWIEEWKHQ LSEKWETADF AFAGGLSAWC MRILPEPQRS
     RWARLFV
//