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Database: UniProt
Entry: Q4WSZ4_ASPFU
LinkDB: Q4WSZ4_ASPFU
Original site: Q4WSZ4_ASPFU 
ID   Q4WSZ4_ASPFU            Unreviewed;      2125 AA.
AC   Q4WSZ4;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-SEP-2017, entry version 92.
DE   SubName: Full=Calcium channel subunit Cch1 {ECO:0000313|EMBL:EAL90438.1};
GN   ORFNames=AFUA_1G11110 {ECO:0000313|EMBL:EAL90438.1};
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL90438.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL90438.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S.,
RA   Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.,
RA   Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S.,
RA   Farman M., Fedorova N., Fedorova N., Feldblyum T.V., Fischer R.,
RA   Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A.,
RA   Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.,
RA   Haas H., Harris D., Horiuchi H., Huang J., Humphray S., Jimenez J.,
RA   Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S.,
RA   Kulkarni R., Kumagai T., Lafon A., Latge J.P., Li W., Lord A., Lu C.,
RA   Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M.,
RA   Mouyna I., Mulligan S., Murphy L., O'Neil S., Paulsen I.,
RA   Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M.,
RA   Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S.,
RA   Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J.,
RA   White O., Woodward J., Yu J.H., Fraser C., Galagan J.E., Asai K.,
RA   Machida M., Hall N., Barrell B., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003808};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003808}.
CC   -!- SIMILARITY: Belongs to the calcium channel alpha-1 subunit
CC       (TC 1.A.1.11) family. {ECO:0000256|RuleBase:RU003808}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAL90438.1}.
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DR   EMBL; AAHF01000004; EAL90438.1; -; Genomic_DNA.
DR   RefSeq; XP_752476.1; XM_747383.1.
DR   ProteinModelPortal; Q4WSZ4; -.
DR   STRING; 5085.CADAFUBP00001034; -.
DR   EnsemblFungi; CADAFUAT00006842; CADAFUAP00006842; CADAFUAG00006842.
DR   GeneID; 3510358; -.
DR   KEGG; afm:AFUA_1G11110; -.
DR   EuPathDB; FungiDB:Afu1g11110; -.
DR   HOGENOM; HOG000207330; -.
DR   InParanoid; Q4WSZ4; -.
DR   KO; K21864; -.
DR   OMA; MLGDSAM; -.
DR   OrthoDB; EOG092C00XX; -.
DR   Proteomes; UP000002530; Chromosome 1.
DR   GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR002077; VDCCAlpha1.
DR   Pfam; PF00520; Ion_trans; 4.
DR   PRINTS; PR00167; CACHANNEL.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|RuleBase:RU003808};
KW   Calcium channel {ECO:0000256|RuleBase:RU003808};
KW   Calcium transport {ECO:0000256|RuleBase:RU003808};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002530};
KW   Ion channel {ECO:0000256|RuleBase:RU003808};
KW   Ion transport {ECO:0000256|RuleBase:RU003808};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003808};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003808}.
FT   TRANSMEM    345    364       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    385    409       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    500    519       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    557    577       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    668    686       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    692    722       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    763    779       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    791    812       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    824    842       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    854    877       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    884    906       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    960    983       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1192   1218       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1233   1255       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1264   1283       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1324   1348       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1445   1466       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1525   1545       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1557   1575       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1587   1606       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1612   1630       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1642   1666       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1742   1761       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1780   1815       EF-hand. {ECO:0000259|PROSITE:PS50222}.
SQ   SEQUENCE   2125 AA;  240370 MW;  860BF460D0D9CADA CRC64;
     MASNSHNRGH NEDNAPTDQS IPLQDLSGPL ERNPSRTSRV GNRFLSRRSL RRGGSLSNYE
     KVSEESPVEP PPVARRARPQ QAGHGNEDEF HIEDPGTFAQ AMSAVGLSFD PTHSTTTSAR
     RRESSSDLIN VPLDDFGPQE AEHYLSPTDT YEDTAPLTDH RFLQPISGAS QNFSGGQDDR
     GSTHGNRFPS DSRPESRLGD DLPHLESGLG RRRRGSSSAG DSRARSLSPS ATGSALQRAG
     SMMKSMSQRV VNLSNEPEVV EQAIMREEQH KNARLEEPPS LPSLSGYAHD APSVGMSDDQ
     LPRTGTSASK AWRMYNNPLR GKALGILGPN NLIRVWLCDI LVHPFMEPFI LVVIIIQTIL
     LALESAKSVW DHPRSVRWGS NPMDYAYFVI FVIYTLELVA KILVSGFIIN PAEYSTLDRS
     MGLRKAIAEK GKNLLAPQRQ FASKQQASSS PEPQQASIIR TFTGGFDQLQ PEVIDDPLQP
     RRVRLAHRAF LRHSFNRLDF VAVVAFWVSF LLSFTGVETH HQLYVFRMLS CLRILRLLAL
     TNGTSVILRS LKKAAPLLVH VAFLIGFFWL LFAIVGIQSF KSSLRRTCRW LGRDNETDFD
     LNDPYGTLQF CGGYLNVTTG AKEPWLKSDL TPSNGDAKGY ICPQGSICVE NTNPYGGTVN
     FDNILHSLEL VFVIMSSNTF SDILYYTTDS DYLAAALFFA FGIVILSLWL VNLLVAVITH
     SFQVIREESK RSAFAVQKLD SLDTENTSTR KTSSFKRFYD RTEWLWIGII ILDLVVQAMR
     SSTMEEDRAN LINVVEVFVT IILLFEIILR FASDWRRFHR SRRNWVDLGL ALITCVIQIP
     AIKHSGRPYD VLTLFQILRV YRVVLAFSVT RNLIMVVFRN ATGLLNLIMF VFLITFLASI
     FATQLFRGQI PAENNGGDEI DINFADIYNS FLGMYQILSS ENWTTMLYDA TAFTYPFNTA
     WISAIFIILW FIVANFIVLN MFIAVIQESF DVSEDEKRLQ QVRAFLEQKQ VTGNSQGNLS
     LSKILMLGRD SNRYRDPLDH GPAALEMLLK DAVVREFLDE QEAPTESRRR DSAPLETAAA
     ATAETVRPGV FSRWWTAITT SVLRREPNPF YSKLKFSRAY EELDPKEMAK EVVSAAEQRK
     RAQREYLMRH PNYNKSLFIF APDNPVRRLC QRIVGPGRGH QRVEGVDPYK PVWYTFSAFV
     YAAIVAMVLI ACITTPIYQR NYQVQWHGEA MPWYVYTDTG FAILFTIEAL IKVIADGFFW
     TPNAYFRGSW GFIDGIVLIT LWINVGSSLF KDWGVSRAIG AFKALRALRL LNVSDSAKDT
     FHSVIIVGGW KVIAAALVSV SFLIPFAIYG VTLYNGQMVK CNDGSIVGSL DQCINEYLSS
     PYNWDVLAPR VASNPFYDFD NFGDALFILF QIVSQEGWID VQNSAMSITG KDMQPQSFAA
     PANGLFFIMF NLLGAVFVLT LFVSVFMRNY TEQTGVAFLT AEQRSWLELR KLLRQISPSK
     RSLDRKSSKW KLWCYRIAVK KHGRWARCVT VILVLHLLLL VLEFYPEPYL WELTRQALFF
     AFTFFYIANV LIRLLGLGWH RFSRSSWDLY SLVAVPGTFV TTILNYLLRN QVIMELNKLF
     LVSITLLLIP RNNQLDQLFK TAAASLTAIG NLLATWFVLF LVYAIALNQA FGLTKFGGNE
     NNNINFRDIP RALILLFRMS CGEGWNELME DFATMVPPFC TYDSDFFNDD CGSAAWARPL
     FISWNIISMY IFVSLFVSLI FESFSYVYQR SSGLYAISRE EIRRFKQAWA TFDPDGTGYI
     TKEQFPRLLG ELSGDFAMRI YDDEFTIGRI LEKCRVDKRD SLIAHRRVVE GLDLDKLCRI
     LRQIPVETVR KRRQRLNRFY EEVLVSADPV RGISFHSILM ILAHYNVISD SKSLRLEEFL
     RRRARLQRVE EAVRRNTVIG FFDTLYWSRE FRRKVNAKKS SRMSEVPQFT VPEIFVDDGY
     QEGSGTAEVG GGGSLGAPDA IVSGDEDTQP MLSPISPTRG PSSPTSSRQL PRLDTNLTGR
     MSNVSSPTEW SSISPSLTPG GRERSHTLSS YDAGPDVPIS PTGSNHSREN SAMNVQDVMQ
     SLDDSAWGES IRRSFTQRRS NGSQP
//
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