ID   Q4X0P4_ASPFU            Unreviewed;       946 AA.
AC   Q4X0P4;
DT   05-JUL-2005, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2005, sequence version 1.
DT   27-MAR-2024, entry version 80.
DE   SubName: Full=von Willebrand domain protein {ECO:0000313|EMBL:EAL93571.1};
GN   ORFNames=AFUA_2G12780 {ECO:0000313|EMBL:EAL93571.1};
OS   Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 /
OS   Af293) (Neosartorya fumigata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879 {ECO:0000313|EMBL:EAL93571.1, ECO:0000313|Proteomes:UP000002530};
RN   [1] {ECO:0000313|EMBL:EAL93571.1, ECO:0000313|Proteomes:UP000002530}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100
RC   {ECO:0000313|Proteomes:UP000002530};
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.,
RA   Fedorova N., Fedorova N., Feldblyum T.V., Fischer R., Fosker N., Fraser A.,
RA   Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B., Haas H., Harris D., Horiuchi H.,
RA   Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K.,
RA   Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafon A., Latge J.P.,
RA   Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y.,
RA   Molina M., Monod M., Mouyna I., Mulligan S., Murphy L., O'Neil S.,
RA   Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A.,
RA   Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H.,
RA   Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M.,
RA   Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D.,
RA   Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G.,
RA   Vazquez de Aldana C.R., Weidman J., White O., Woodward J., Yu J.H.,
RA   Fraser C., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.,
RA   Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAL93571.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAHF01000001; EAL93571.1; -; Genomic_DNA.
DR   RefSeq; XP_755609.1; XM_750516.1.
DR   AlphaFoldDB; Q4X0P4; -.
DR   STRING; 330879.Q4X0P4; -.
DR   EnsemblFungi; EAL93571; EAL93571; AFUA_2G12780.
DR   GeneID; 3513530; -.
DR   KEGG; afm:AFUA_2G12780; -.
DR   VEuPathDB; FungiDB:Afu2g12780; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_003826_2_0_1; -.
DR   InParanoid; Q4X0P4; -.
DR   OMA; QRAIMTT; -.
DR   OrthoDB; 4178950at2759; -.
DR   Proteomes; UP000002530; Chromosome 2.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR   PANTHER; PTHR45737:SF6; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN DDB_G0286969-RELATED; 1.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002530}.
FT   DOMAIN          11..142
FT                   /note="VIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51468"
FT   DOMAIN          294..470
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          734..755
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   946 AA;  103296 MW;  AD545F70095E4B4F CRC64;
     MIGGRVTYLC GCSYYTHPQA KPVYLPRIGI KVHATILSSV SRTVLTQTYT NPSKNPLEEV
     SYTFPLYDGV SVVGFNCLIG DRTLHSRVKP RKQAKAEYDD AVSKGESAAL MAHSLSASDV
     LSIRLGNVGP GETVVVEITL VGELKQDAQS DAVRYTLPNS IAPRYGYHPG NMSMPPEADV
     QGISITLDVQ MESTAVIREI QSTSHSLSVA LGRVSASASG SSGSDKAFNP AQASVSVNLK
     EDWTALARDF VLLVKADGLD TPRAMLETHP VIPTQRAIMT TLVPKFGLEP IKPEIIFVID
     RSGSMMDKID TLKSALRVFL KSLPVGVCFN ICSFGSRHSF LWKQSLFYTA ESLQEALSFV
     DGVRANMGGT EMQEAVEATV RSRMKDKELE VLILTDGQIW NQQTLFGFIR ETAADNGARF
     FSLGIGNGAS HSLVEGIARA GNGFSQMVVN YEELDRKVVR MLKGALTPHI FDYKLEIEHD
     DPVEEFEVVL PERPRAMPVD EAEMKQQPIS LFDADYKEDE QKTDEEALPV LTPPQTLQAP
     YKIPPLYPFI RTTAYLLGSA NMQNPKALIF RATSKQGPLV LRIPINDIGT GETIHQLAVR
     RAMIELEEGH GWLAAATSNG NSFDNLHPTS KERIIARECE KLGTQFQVTG KRCSFIALEK
     DSTSDQEKET DIANLPTSKA TGEEGAVYQA SGAVPGPPHA RCRRLASKAH RMIAPSPRPP
     PPSQGTPFSA SLLARKAPKS SLSSEQGWAK APTAREVPES LFGAPGIAKF VDTRVSQPPP
     PAPKRGYGFN AQMDPTVCPP AGPAHVSDLM EMDGAVGYTL ASPILSSTFS NETAGAASQV
     HRIIALQSFE GYWTWSEELM NALRLDERDV RAQLMKLFQK DSRGSNLTVI ATMLAMAYLS
     THCAAHRSVW ELVYDKAEGW KRQQLVEMGE TGSVLKAKEN EITALV
//