ID Q50J24_PLAAG Unreviewed; 951 AA.
AC Q50J24;
DT 07-JUN-2005, integrated into UniProtKB/TrEMBL.
DT 07-JUN-2005, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Peptide synthetase {ECO:0000313|EMBL:CAG38892.1};
DE Flags: Fragment;
GN Name=mcyA {ECO:0000313|EMBL:CAG38892.1};
OS Planktothrix agardhii No39.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Planktothrix.
OX NCBI_TaxID=282418 {ECO:0000313|EMBL:CAG38892.1};
RN [1] {ECO:0000313|EMBL:CAG38892.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=No39 {ECO:0000313|EMBL:CAG38892.1};
RA Kurmayer R., Christiansen G., Gumpenberger M., Fastner J.;
RT "Genetic identification of microcystin ecotypes in toxic cyanobacteria of
RT thegenus Planktothrix.";
RL Microbiology (Mosc.) 151:1525-1533(2005).
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DR EMBL; AJ749251; CAG38892.1; -; Genomic_DNA.
DR AlphaFoldDB; Q50J24; -.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR CDD; cd17646; A_NRPS_AB3403-like; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 881..951
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAG38892.1"
FT NON_TER 951
FT /evidence="ECO:0000313|EMBL:CAG38892.1"
SQ SEQUENCE 951 AA; 107604 MW; 2951B56F14BD9B9C CRC64;
GICLERSLEL VVGLLAILKA GGAYVPIDPH YPQERLTYLL ADTQVKILLT SQSLTSLLPA
NLAKIICLDS DWDLIAKENP DNFESGVTVE NLAYVIYTSG STGQPKGAMN CHRGVVNRLL
WMQDTYPLTQ GDRILQKTPF SFDVSVWEFF CPLLTGARLV VAKPEGHKDS VYLIKLIQDQ
QITTLHFVPS MLRVLLQEAD LEKCQSLKRV ICSGEALPND LSQRFFERFN CELHNLYGPT
EAAIDVTYWA CSPNWKREVV PIGRPVANTQ IYLLNADLQP VPIGVVGELH IGGVQLARGY
FNRPELTAEK FIANPFYPSL QKEQGSTISP RLYKTGDLTR YLPDGNIEFL GRLDHQVKIR
GFRIELGEIE TILGQHPDVC QSVVLAHQTE TGSQTLIAYV VSQSQTRQHL SPEQEPHFFD
EQIGQWQTLY NQTYRQSVED SNPLFNTVGW NSSYTGEPIP AAEMDEWLKD KTATILAHRP
QRVLEIGCGT GLILFQVAPH CDRYWGTDIS VVGLDLIRHH LGESKLDLAE QVNLLQRPAD
DFEGLEAEAF DTIILNSVVQ YFPHIDYLVK VLEKAIAAIA PGGRIFLGDV RNLKLLAAFH
ASVELTKADP DISVDQWQKR VERQIAQEQE LLIDPAFFTA LQQRFPQITQ VDIQLPRSQY
ENELTQFRYN VVLQINTKAE VEQSETWLAQ EAFTIPELSH LLEKTQPPVV GIKGLTNLKL
VAPLTILEFF KHPQDVQTVE TLQSSLQKLV LPNPETELDQ LAETFGYSLL LTYADSQTLN
HYDAIFVKEQ RRKPHRAKLT NLSKTHQDWQ QYANHPLQPQ LNRQLIPQLR SYLETRLPEY
MIPNAFVLLA EIPLTPNGKL DRRALPSPEQ IRLELTDTFV APCTPIEEML ALIWAEILGL
EQIGIHDNFF ELGGDSIRGI QVIAKARTMG FEFSLPELLQ HQTIQELAHL V
//
