ID   Q53049_9NOCA            Unreviewed;       562 AA.
AC   Q53049;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=PHA synthase {ECO:0000313|EMBL:CAA47035.1};
GN   Name=phbCRr {ECO:0000313|EMBL:CAA47035.1};
OS   Rhodococcus ruber.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=1830 {ECO:0000313|EMBL:CAA47035.1};
RN   [1] {ECO:0000313|EMBL:CAA47035.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIMB40126 {ECO:0000313|EMBL:CAA47035.1};
RX   PubMed=1526467; DOI=10.1016/0378-1097(92)90459-2;
RA   Pieper U., Steinbuchel A.;
RT   "Identification, cloning and sequence analysis of the poly(3-
RT   hydroxyalkanoic acid) synthase gene of the gram-positive bacterium
RT   Rhodococcus ruber.";
RL   FEMS Microbiol. Lett. 75:73-79(1992).
RN   [2] {ECO:0000313|EMBL:CAA47035.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NCIMB40126 {ECO:0000313|EMBL:CAA47035.1};
RA   Steinbuechel A.;
RL   Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; X66407; CAA47035.1; -; Genomic_DNA.
DR   PIR; S25725; S25725.
DR   RefSeq; WP_017681423.1; NZ_LRRL01000024.1.
DR   SMR; Q53049; -.
DR   ESTHER; rhoru-PHBCRR; PhaC_cen_dom.
DR   GeneID; 66836221; -.
DR   KEGG; rrz:CS378_04625; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0042619; P:poly-hydroxybutyrate biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR010941; PhaC_N.
DR   PANTHER; PTHR36837; POLY(3-HYDROXYALKANOATE) POLYMERASE SUBUNIT PHAC; 1.
DR   PANTHER; PTHR36837:SF2; POLY(3-HYDROXYALKANOATE) POLYMERASE SUBUNIT PHAC; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF07167; PhaC_N; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          72..240
FT                   /note="Poly-beta-hydroxybutyrate polymerase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07167"
FT   DOMAIN          242..480
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   562 AA;  61459 MW;  7EB27CB285A01E06 CRC64;
     MLDHVHKKLK STLDPIGWGP AVTSVAGRAV RNPQAVTAAT AEYAGRLAKI PAAATRVFNA
     NDPDAPMPVD PRDRRFSDTA WQENPAYFSL LQSYLATRAY VEELTEAGSG DPLQDGKARQ
     FANLMFDALA PSNFLWNPGV LTRAFETGGA SLLRGARYAA HDILNRGGLP LKVDSDAFTV
     GENLAATPGK VVFRNDLIEL IQYAPQTEQV HAVPILAAPP WINKYYILDL APGRSLAEWA
     VQHGRTVFMI SYRNPDESMR HITMDDYYVD GIATALDVVE EITGSPKIEV LSICLGGAMA
     AMAAARAFAV GDKRVSAFTM LNTLLDYSQV GELGLLTDPA TLDLVEFRMR QQGFLSGKEM
     AGSFDMIRAK DLVFNYWVSR WMKGEKPAAF DILAWNEDST SMPAEMHSHY LRSLYGRNEL
     AEGLYVLDGQ PLNLHDIACD TYVVGAINDH IVPWTSSYQA VNLLGGDVRY VLTNGGHVAG
     AVNPPGKRVW FKAVGAPDAE SGTPLPADPQ VWDEAATRYE HSWWEDWTAW SNKRAGELVA
     PPAMGSTAHP PLEDAPGTYV FS
//