ID Q536X6_9CICH Unreviewed; 334 AA.
AC Q536X6;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE SubName: Full=Putative violet sensitive visual pigment {ECO:0000313|EMBL:AAV93287.1};
DE Flags: Fragment;
GN Name=SWS1 {ECO:0000313|EMBL:AAV93287.1};
OS Pundamilia azurea.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303519 {ECO:0000313|EMBL:AAV93287.1};
RN [1] {ECO:0000313|EMBL:AAV93287.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=16313597; DOI=10.1111/j.1365-294X.2005.02735.x;
RA Carleton K.L., Parry J.W., Bowmaker J.K., Hunt D.M., Seehausen O.;
RT "Colour vision and speciation in Lake Victoria cichlids of the genus
RT Pundamilia.";
RL Mol. Ecol. 14:4341-4353(2005).
CC -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC mediate vision. They consist of an apoprotein, opsin, covalently linked
CC to cis-retinal. {ECO:0000256|ARBA:ARBA00002881}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU004951}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004951}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family. Opsin
CC subfamily. {ECO:0000256|RuleBase:RU004951}.
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DR EMBL; AY673730; AAV93287.1; -; Genomic_DNA.
DR AlphaFoldDB; Q536X6; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001760; Opsin.
DR InterPro; IPR001521; Opsin_blue.
DR InterPro; IPR027430; Retinal_BS.
DR PANTHER; PTHR24240; OPSIN; 1.
DR PANTHER; PTHR24240:SF16; SHORT-WAVE-SENSITIVE OPSIN 1; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00238; OPSIN.
DR PRINTS; PR00574; OPSINBLUE.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS00238; OPSIN; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991, ECO:0000256|RuleBase:RU004951};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU004951};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004951};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543,
KW ECO:0000256|RuleBase:RU004951};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004951};
KW Retinal protein {ECO:0000256|ARBA:ARBA00022925,
KW ECO:0000256|RuleBase:RU004951};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606,
KW ECO:0000256|RuleBase:RU004951};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU004951};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004951};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004951}.
FT TRANSMEM 29..54
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 66..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 94..123
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 144..165
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 195..215
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 246..269
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004951"
FT DOMAIN 46..298
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAV93287.1"
SQ SEQUENCE 334 AA; 37265 MW; C3BD888F418D000B CRC64;
GKHFHLYENI SKVSPFEGPQ YYLAPVWAFY LQAAFMGFVF FAGTPLNFIV LVATMKYKKL
RVPLNFILVN ISFSGFIFVT FSVSQVFLAS MRGYYFLGHT LCALEAAVGS VAGLVTAWSL
AVLSFERYLV ICKPFGAFRF GSNHALAAVA FAWFMGVSCA CPPFFGWSRY IPEGLGCSCG
PDWYTHNEQY NTTSYIHFLM VTCFIMPLSI IIFCYSQLLG ALRAVAAQQA ESASTQKAEK
EVSRMIIVMV GSFVTCYGPY ALAALYFAYS TDENKDYRLV TIPAFFSKSA CVYNPLIYVF
MNKQFNGCIM EMVFGKTMDE SSEVSTKTEV STAS
//
