ID Q54483_SERMA Unreviewed; 1036 AA.
AC Q54483;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 2.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=SSP-h1 {ECO:0000313|EMBL:BAA33455.1};
OS Serratia marcescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=615 {ECO:0000313|EMBL:BAA33455.1};
RN [1] {ECO:0000313|EMBL:BAA33455.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=IFO3046 {ECO:0000313|EMBL:BAA33455.1};
RX PubMed=9192732;
RA Ohnishi Y., Beppu T., Horinouchi S.;
RT "Two genes encoding serine protease homologues in Serratia marcescens and
RT characterization of their products in Escherichia coli.";
RL J. Biochem. 121:902-913(1997).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; D78380; BAA33455.1; -; Genomic_DNA.
DR PIR; JC5568; JC5568.
DR AlphaFoldDB; Q54483; -.
DR MEROPS; S08.094; -.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04848; Peptidases_S8_Autotransporter_serine_protease_like; 1.
DR Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR005546; Autotransporte_beta.
DR InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR InterPro; IPR013425; Autotrns_rpt.
DR InterPro; IPR006315; OM_autotransptr_brl_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034061; Peptidases_S8_Autotransporter.
DR NCBIfam; TIGR01414; autotrans_barl; 1.
DR NCBIfam; TIGR02601; autotrns_rpt; 1.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF03797; Autotransporter; 1.
DR Pfam; PF12951; PATR; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00869; Autotransporter; 1.
DR SUPFAM; SSF103515; Autotransporter; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 759..1036
FT /note="Autotransporter"
FT /evidence="ECO:0000259|PROSITE:PS51208"
FT ACT_SITE 92
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 149
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 367
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1036 AA; 107598 MW; 0843C2A273FF2685 CRC64;
MEKKLRGVKS ARAAFGWPEI GVHRAQWSAM LICLTAIGGA QASSYIENGK AGDPASWRSS
EFNAEWGLGA IHADQAYAAG YTGKGIKLGI FDQPVYAKHP EFAGENKVIN LVTEGIREYT
DPYIPVKKGD AFRYDGTPSV DSDGTLGSHG THVGGIAAGS RDGGAMHGVA FNAQIISAEN
GDPGPEDGII LGNDGAVYQA GWDALVASGA RIINNSWGIG ITEKFDEGGY DPAYPHFTVN
DAQKQFDQIK QILGTKPGGA YQGAIDAARS GVVTIFAAGN DGNLNNPDAM AGLAYFVPDI
APNWLSVASL QDPTNTGDYS ISTFSSRCGY TASLCVSAPG TRVYSSIIEG TSVENLTTGY
AKYSGTSMAA PHVAGSVAVL MERFPYLNGA QVAEVLKTTA TDMGAPGIDA LYGWGMINLG
KAINGPGMLV TAEDIPEEFR IPDPTGVAYG PTQFVVDLPG VGAVLDKGKP TERVCSDVLC
GLDFWSNDIS GHGGLTKQGI GTLVLTGNNT YSGPTLVNQG RLAINGSVTS AVSVQSGGIV
GGSGTVGSLT ARRGGTVAPG NSIGTLNVAG DVSFEPGSRY AVEVGPNGQS DRIQSGGAAT
IGGGEVAVTL ENSSNLLTQS EVRSLLGQQY TILSAQQGVS GQFDAVAPNY LFLGTGLSYQ
PTGVTLSVGR NGTSFASVAQ TPNERAVAAA ADALAAGNPV YESLLNSGTA GEARQAFRQL
SGQIHADIAS ALVNDSRYLR EALNGRLRQA EGLASSSAIK ADEDGAWAQL LGAWDHASGD
ANATGYQAST YGVLVGLDSA AAADWRLGVA TGYTRTSLHG GYGSKADSDN YHLAAYGDKQ
FGALALRGGA GYTWHRIDTK RSVNYGMQSD RDTAKYSART EQLFAEAGYS VKGEWLNLEP
FVNLAYVNFE NNGIAESGGA AALRGDKQHT DATVSTLGLR ADTEWQVSPG TTVALRSELG
WQHQYGGLER GTGLRFNGGN APFVVDSVPV SRDGMVLKAG AEVAVNENAS LSLGYGGLLS
QNHQDNSVNA GFTWRF
//
