ID Q54B40_DICDI Unreviewed; 886 AA.
AC Q54B40;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=DDB_G0293924 {ECO:0000313|EMBL:EAL60461.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL60461.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL60461.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL60461.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL60461.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFI02000224; EAL60461.1; -; Genomic_DNA.
DR RefSeq; XP_628876.1; XM_628874.1.
DR AlphaFoldDB; Q54B40; -.
DR PaxDb; 44689-DDB0192199; -.
DR GeneID; 8629492; -.
DR KEGG; ddi:DDB_G0293924; -.
DR dictyBase; DDB_G0293924; -.
DR eggNOG; ENOG502R7KW; Eukaryota.
DR HOGENOM; CLU_325550_0_0_1; -.
DR InParanoid; Q54B40; -.
DR OMA; AFSRNHN; -.
DR Proteomes; UP000002195; Chromosome 6.
DR GO; GO:0016607; C:nuclear speck; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13952; U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 16..95
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 121..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 493..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..555
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 886 AA; 96618 MW; D59B0554E8DFD7C5 CRC64;
MNDTPLSSNL IDRTSSTIYV SNIRHSTPIN SIFNIFSKFG PLERCEIPEN KFGKTRGFAF
IEFENKANAY TAFEELAKQE ILLDGRVLKL EWARATKLYK EDIQNLSSES KEKIMGAFSR
NHNFDSRYSK KGAPTNSSNN TRKTNGGGIS KSVNNNNNNN NNNNNNNNNT NNNNNNNNNN
NNNNNNNNNN NNNNNNNNNN NNNNNIINNT PINGGIHSSS SSSTIIQSTN NSIASNNNTL
ASVLSNSNSN PLPSSSSQAS SSSTPLTIQS STSNNNNNNN NNNNNNNNNN NNNNNNNNIS
SNVLTNNVIN GVGRITSSPS FTSSSNINNN NNNNNNNNNN NNNNNNNVNH SPASLGLNNN
NNNNNNNINC NGFLNIMGTN NNCNSFDLNL TSLGNSMVNI PLSPSRSPLC NLSNSPSSSS
SSSSSPPSLS QQQQQQQQQQ QQQQQQQILT PKKKMISTSN GGTFIKKEDT SPLLSNSNIS
YYQYTQQQQQ QQQLQQQQQL NGVTQSPTQS PIKKYNSIAS NGNGVHHNSL NGSMNHYHQQ
QQHQHHHHHH HHHNNNNMIS SSVNGTTSTN PLLPLPLSST THSLSKSLNG TTSSGINDLH
HQQQHISNYG QYFGIPNFNQ SVDFNLSFNH TITNLSNLDL RGINISDNIN SSSNSGSTSS
SSITTSSLSI NNNNNTNNNN NNNNNIIINN SNGSSPNSSS PAINNGTSTI GGSSSTLSSS
TNGNSLKQIA GGGSSSSSSS SSSSTTSSPT TPLTNNINTN FTNHLQNGLF NDELRYLSEF
NASLFVVNNN NINNNNNNSN TNGFSNFSTT TNGNHDLLSQ PALSHNHNQQ QHHNLHHLHH
QHHYFASNQD PVYVSSPPGI NSFTHFSNSP ISNFNNNSPF FKSNFN
//
