ID CTSL2_DICDI Reviewed; 567 AA.
AC Q54GB2;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 01-MAY-2013, entry version 41.
DE RecName: Full=CTD small phosphatase-like protein 2;
DE Short=CTDSP-like 2;
DE EC=3.1.3.-;
GN Name=ctdspl2; ORFNames=DDB_G0290365;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A.,
RA Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q.,
RA Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F.,
RA Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P.,
RA Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P.,
RA Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N.,
RA Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M.,
RA Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I.,
RA Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R.,
RA Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C.,
RA Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D.,
RA Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S.,
RA Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T.,
RA Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A.,
RA Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M.,
RA Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G.,
RA Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Probable phosphatase (By similarity).
CC -!- SIMILARITY: Belongs to the CTDSPL2 family.
CC -!- SIMILARITY: Contains 1 FCP1 homology domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AAFI02000162; EAL62309.1; -; Genomic_DNA.
DR RefSeq; XP_635771.1; XM_630679.1.
DR HSSP; Q9GZU7; 1T9Z.
DR ProteinModelPortal; Q54GB2; -.
DR EnsemblProtists; DDB0238050; DDB0238050; DDB_G0290365.
DR GeneID; 8627575; -.
DR KEGG; ddi:DDB_G0290365; -.
DR dictyBase; DDB_G0290365; ctdspl2.
DR eggNOG; COG5190; -.
DR OMA; WFEDEND; -.
DR ProtClustDB; CLSZ2728785; -.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR GO; GO:0016311; P:dephosphorylation; IEA:GOC.
DR Gene3D; 3.40.50.1000; -; 1.
DR InterPro; IPR011948; Dullard_phosphatase.
DR InterPro; IPR023214; HAD-like_dom.
DR InterPro; IPR004274; NIF.
DR Pfam; PF03031; NIF; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like_dom; 1.
DR TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 3: Inferred from homology;
KW Complete proteome; Hydrolase; Protein phosphatase; Reference proteome.
FT CHAIN 1 567 CTD small phosphatase-like protein 2.
FT /FTId=PRO_0000331473.
FT DOMAIN 386 544 FCP1 homology.
FT COMPBIAS 31 36 Poly-Gln.
FT COMPBIAS 44 47 Poly-Lys.
FT COMPBIAS 72 79 Poly-His.
FT COMPBIAS 134 141 Poly-Ser.
FT COMPBIAS 142 146 Poly-Asn.
FT COMPBIAS 231 240 Poly-Asn.
FT COMPBIAS 256 267 Poly-Gln.
FT COMPBIAS 313 325 Poly-Thr.
FT COMPBIAS 349 359 Poly-Glu.
SQ SEQUENCE 567 AA; 63950 MW; 1CCDEF91246F1ADF CRC64;
MSSGLKTQTT IDILHDHSVE SSSDHLYILK QQQQHQHEDT DSPKKKKLRH QCEETSQYIV
PSLNDEVDDL GHHHLHHHHV NNINNSLLKQ GLSALSSLSA SSTSSISPSS SQSSSPLKQS
ERSIATSIDS MNDSTSSSSS SNNNNNFSSV PSHNIYTPSC LLSNLNNDTD SIIPNMNGST
DGDGGDIRRE KVDENDEEVL CNDNHLSKDN EQEDNMVSFL NESNEEVIQT NNNNNNDNNN
SSNICINNFC NINNNQQQQQ QQQQQQQNNV NSSIILEDSN KENKTESNNS NSNSNSSPSF
FHNLQQHPTS AATTTTTTTT TITTTSATTS IIIKEDNSDD EIDDECDDES EEEEEDEEEF
NPFLFIKQLA NATTMPPPVA LPPKEHSSPK ISLVLDLDET LVHCSTEPLE QPHLTFPVFF
NNTEYQVFAK KRPFFEEFLH KVSDIFEVII FTASQEVYAN KLLNMIDPNN KIKYRLYRDS
CVYVDGNYLK DLSVLGRDLK QVVIIDNSPQ SFGFQVDNGI PIESWFEDEN DKELLQLVPF
LESLTNVEDV RPHIRDKFKL YQLISQA
//
