ID Y4753_DICDI Reviewed; 464 AA.
AC Q54P72;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 06-MAR-2013, entry version 36.
DE RecName: Full=Probable acid phosphatase DDB_G0284753;
DE EC=3.1.3.2;
GN ORFNames=DDB_G0284753;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A.,
RA Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q.,
RA Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F.,
RA Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P.,
RA Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P.,
RA Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N.,
RA Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M.,
RA Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I.,
RA Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R.,
RA Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C.,
RA Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D.,
RA Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S.,
RA Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T.,
RA Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A.,
RA Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M.,
RA Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G.,
RA Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CATALYTIC ACTIVITY: A phosphate monoester + H(2)O = an alcohol +
CC phosphate.
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
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DR EMBL; AAFI02000071; EAL65029.1; -; Genomic_DNA.
DR RefSeq; XP_638386.1; XM_633294.1.
DR HSSP; P15309; 1ND5.
DR ProteinModelPortal; Q54P72; -.
DR EnsemblProtists; DDB0186172; DDB0186172; DDB_G0284753.
DR GeneID; 8624755; -.
DR KEGG; ddi:DDB_G0284753; -.
DR dictyBase; DDB_G0284753; -.
DR eggNOG; NOG235758; -.
DR InParanoid; Q54P72; -.
DR ProtClustDB; CLSZ2430220; -.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:EC.
DR InterPro; IPR000560; His_Pase_superF_clade-2.
DR Pfam; PF00328; His_Phos_2; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
DR PROSITE; PS00778; HIS_ACID_PHOSPHAT_2; FALSE_NEG.
PE 3: Inferred from homology;
KW Complete proteome; Hydrolase; Reference proteome.
FT CHAIN 1 464 Probable acid phosphatase DDB_G0284753.
FT /FTId=PRO_0000369256.
FT COMPBIAS 18 27 Poly-Gly.
FT ACT_SITE 81 81 Nucleophile (By similarity).
FT ACT_SITE 347 347 Proton donor (By similarity).
SQ SEQUENCE 464 AA; 53626 MW; 90176186B58DFB51 CRC64;
MFSYFRKSQQ KVEENQNGGG GDGRGSGIKV ELQTNINSRD LKNEHSDPKF KFSPLRSTDV
HLEDYDNEKY KLKFIQIVTR HGRRTPESNR TPLTMWMCNS MDHLISNKDS PRPNCNPGQL
TVLGIVDQIN VGKIYRKLFI DHLGFLDSQY NKDQIFIRST NTTRTISSAR SLMHGLYGGS
FTDEQEKSPH HSSFLVKPDN EENMYPRNSK KLVFLKNLIK QHPKVIKENQ LSELEKFTEK
INKIFENSKP EESSFRARGF RSYAGLVNSF DCFRNNGLPI PKGLTKDIIQ RMYEESAKEF
KSARYFPEMS ILGIGRFVDD LNKELKLKAR NDPSVKDLKL SLYSGHDTTL AALLVGYDMY
EDKIHPVTSS TLEFLLMQDK DYKEPEVVKI TKSIEKELIN HQYVKVIYNH KPIHIGPCKD
KEVDGMCPLS EFLKISQSII PTNYDEQSKL TQLDKKRYLS LIED
//
