ID Q54PW3_DICDI Unreviewed; 907 AA.
AC Q54PW3;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE RecName: Full=4-alpha-glucanotransferase {ECO:0000256|ARBA:ARBA00012560};
DE EC=2.4.1.25 {ECO:0000256|ARBA:ARBA00012560};
DE AltName: Full=Amylomaltase {ECO:0000256|ARBA:ARBA00031423};
DE AltName: Full=Disproportionating enzyme {ECO:0000256|ARBA:ARBA00031501};
GN ORFNames=DDB_G0284259 {ECO:0000313|EMBL:EAL65318.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL65318.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL65318.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL65318.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Transfers a segment of a (1->4)-alpha-D-glucan to a new
CC position in an acceptor, which may be glucose or a (1->4)-alpha-D-
CC glucan.; EC=2.4.1.25; Evidence={ECO:0000256|ARBA:ARBA00000439};
CC -!- SIMILARITY: Belongs to the disproportionating enzyme family.
CC {ECO:0000256|ARBA:ARBA00005684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL65318.1}.
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DR EMBL; AAFI02000064; EAL65318.1; -; Genomic_DNA.
DR RefSeq; XP_638682.1; XM_633590.1.
DR AlphaFoldDB; Q54PW3; -.
DR SMR; Q54PW3; -.
DR STRING; 44689.Q54PW3; -.
DR PaxDb; 44689-DDB0185931; -.
DR GeneID; 8624512; -.
DR KEGG; ddi:DDB_G0284259; -.
DR dictyBase; DDB_G0284259; -.
DR eggNOG; ENOG502QR3V; Eukaryota.
DR HOGENOM; CLU_014132_0_0_1; -.
DR InParanoid; Q54PW3; -.
DR OMA; WTDSYPY; -.
DR PhylomeDB; Q54PW3; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004134; F:4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:2001070; F:starch binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05467; CBM20; 1.
DR CDD; cd05816; CBM20_DPE2_repeat2; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR034841; CBM20_DPE2_2.
DR InterPro; IPR002044; CBM_fam20.
DR InterPro; IPR003385; Glyco_hydro_77.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR32518; -; 1.
DR PANTHER; PTHR32518:SF3; 4-ALPHA-GLUCANOTRANSFERASE; 1.
DR Pfam; PF00686; CBM_20; 2.
DR Pfam; PF02446; Glyco_hydro_77; 1.
DR SMART; SM01065; CBM_2; 2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49452; Starch-binding domain-like; 2.
DR PROSITE; PS51166; CBM20; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT DOMAIN 1..102
FT /note="CBM20"
FT /evidence="ECO:0000259|PROSITE:PS51166"
FT DOMAIN 134..241
FT /note="CBM20"
FT /evidence="ECO:0000259|PROSITE:PS51166"
SQ SEQUENCE 907 AA; 106077 MW; 26774EA2F27CBA16 CRC64;
MANFIRFKVN YFTRLGQELY VSGSTEPLGN WDESKATKLT YCDNGDWETL IQFPASNNKV
DYKYFVMDTN GEKIWESGSN RTFNLNDLNS NYIHEFRDTY QSPTSAENTY LNSSFFREVL
FGRENPTQYS LIKQTQADKV IIHFQVKSTY VPPNHSIYIV GSNTQLGNWR TDRAVKLSDE
SYPIWKVDLE FSKDQLPFSY KYIIADKIKS VVHWEYGNDR WFTASATHAS EYSSTTNEDR
DFFFNDGEFK DSQLLRSAGV AVPIFSLRSK QGLGIGEFND LHQLVDWSHQ SGLHMIQILP
INDTTVYYTW RDSYPYSSVS VYALHPIYIH IDSITKDPKI LAQVNEHREK LNKLTTVDYE
AVMNLKSKLL REIYSKEKAS LDGNKEFLQF VKDSEDWIKA YALYSVLRDT YKSGDFDQWP
VYSSITPEDI EKESKPNSKY YDDMRYYYFV QFHLHNQLLA ASKYASAKRI GLKGDLPIGV
NRVSVDAWVS PHLFRMNMST GAPPDAFADD GQNWGFPTYN WEVMKKDGYA WWRSRLGQMS
KYFHAFRIDH ILGFFRIWEI PTTCVTGLLG KFNPSLPLWR SELQNNGLWD IDRLTQPYIR
YHTLRELFGE YADSVATKFL VEYSSNCFNM KPEFATERLI EKNLNEEDAM YKSGLFKLVQ
NVSLLADAED ENRFYPRIEI TKTSNFNELS DDIKTILHRL YISYYYERQE ELWAQIALQR
LPLIKGCTKM LVCGEDLGMV PKCVEPVLND LGILGLRIQR MPSDSNKDFY HPNEYSYLTV
NTTSSHDMST LRGWWEEDRA RSQVFYNKIL GMFGDAPYFC EPYVSEAVIT QHLHSQSMIS
IFPIQDWFGI SSEYGSRDPK EEKINEPSNP MHYWRYRMHI NLETLVNDHD FSKNIQRLIL
SSNRNLD
//
