ID SKI8_DICDI Reviewed; 299 AA.
AC Q54S59;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 100.
DE RecName: Full=Superkiller complex protein 8;
DE Short=Ski8;
DE AltName: Full=WD repeat-containing protein 61 homolog;
GN Name=skic8; Synonyms=wdr61; ORFNames=DDB_G0282793;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the SKI8 family. {ECO:0000305}.
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DR EMBL; AAFI02000047; EAL66256.1; -; Genomic_DNA.
DR RefSeq; XP_640180.1; XM_635088.1.
DR AlphaFoldDB; Q54S59; -.
DR SMR; Q54S59; -.
DR STRING; 44689.Q54S59; -.
DR PaxDb; 44689-DDB0267163; -.
DR EnsemblProtists; EAL66256; EAL66256; DDB_G0282793.
DR GeneID; 8623719; -.
DR KEGG; ddi:DDB_G0282793; -.
DR dictyBase; DDB_G0282793; wdr61.
DR eggNOG; KOG4155; Eukaryota.
DR HOGENOM; CLU_000288_57_11_1; -.
DR InParanoid; Q54S59; -.
DR OMA; ERKCLHT; -.
DR PhylomeDB; Q54S59; -.
DR Reactome; R-DDI-429958; mRNA decay by 3' to 5' exoribonuclease.
DR PRO; PR:Q54S59; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0016593; C:Cdc73/Paf1 complex; IBA:GO_Central.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44090; WD REPEAT-CONTAINING PROTEIN 61; 1.
DR PANTHER; PTHR44090:SF1; WD REPEAT-CONTAINING PROTEIN 61; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repeat; WD repeat.
FT CHAIN 1..299
FT /note="Superkiller complex protein 8"
FT /id="PRO_0000328583"
FT REPEAT 11..48
FT /note="WD 1"
FT REPEAT 54..93
FT /note="WD 2"
FT REPEAT 96..135
FT /note="WD 3"
FT REPEAT 138..177
FT /note="WD 4"
FT REPEAT 180..219
FT /note="WD 5"
FT REPEAT 223..263
FT /note="WD 6"
FT REPEAT 266..299
FT /note="WD 7"
SQ SEQUENCE 299 AA; 32355 MW; 58061042B42ECCCD CRC64;
MFQFGKKITG AHEDGIWCVK WQGDIIATGG MGTKVKTWHG NQPQFLTERK VFDKHILGVT
SLDIDIGARY LATGGMDGTV RLFDLSTNTL HKTIDSGPLG CLKIGFLNSA NNLVSVSESG
NISIYSVETG EKLRSISNTN KQVLTMAISP NNEQIAVAGL DGTVLCYDVE SGRRVSEIKA
HGVPIRSLCF SSDSKTIFTG AEDSQIRLHD PNSSNPYIAS LLGHSSFIFS LVASSNGDLL
ASSGSIDRKV CIWDIKTRKL DSSFTAHADQ TWDLAFSPDS TKLVSVSDDC SIHSYALKQ
//
