ID Q54UI7_DICDI Unreviewed; 505 AA.
AC Q54UI7;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=DDB_G0281057 {ECO:0000313|EMBL:EAL66825.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL66825.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL66825.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL66825.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL66825.1}.
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DR EMBL; AAFI02000040; EAL66825.1; -; Genomic_DNA.
DR RefSeq; XP_640789.1; XM_635697.1.
DR AlphaFoldDB; Q54UI7; -.
DR SMR; Q54UI7; -.
DR PaxDb; 44689-DDB0203979; -.
DR GeneID; 8622842; -.
DR KEGG; ddi:DDB_G0281057; -.
DR dictyBase; DDB_G0281057; -.
DR eggNOG; ENOG502RBMQ; Eukaryota.
DR HOGENOM; CLU_540176_0_0_1; -.
DR InParanoid; Q54UI7; -.
DR OMA; CNEPWSG; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0019953; P:sexual reproduction; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..505
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004249872"
FT DOMAIN 103..138
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 420..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 128..137
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 505 AA; 56996 MW; EE7F0A362330686C CRC64;
MIKKNKLLVL IILNFLINSI YSDRPLINYI EPLTRNDNKL SVFGRFFGEK LQDVKVEIDG
KPYKISEWSN SSFEVTLQPP NPKQSKIKVT TPINSVEKEI YFLNENCLGI DVCNGHGICI
KNSTECVCNE PWSGKDCSII TGESMIELVD KPKVYTSTKL NIFKIPEIEN INFNTSFGLV
LKEYTKNDII LNTYLLTPSI QYGSIKGPDL QVYRYRTNTL ISSSDHSFNC DITLTHYQSN
QTKSFYNQYI NELKDSFALS VIINNFIPIS PTNKLTLFIY PMIKSKKSFG GKLSTIVNDN
NNNNKIDEND DGQYINGTTS IKMSIGTQKL RINLYNFGLF SQKFTTFNTS IVEIFNNTNN
INNTNNSDSS DNRVIDNDIY SIISITSNSS KYIYFNADFY PYLDDSENVD SSDKLTLFSD
EESGSSDSIS SSSGSGSSSS SSSDNNTRNI IDDSKHNLTP TQNITTEVNH ENHQNESNSS
SSIGNKLPIS IITYFGPVFI FWKLI
//
