ID Q54X10_DICDI Unreviewed; 361 AA.
AC Q54X10;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Phospholipid/glycerol acyltransferase domain-containing protein {ECO:0000259|Pfam:PF01553};
GN ORFNames=DDB_G0279277 {ECO:0000313|EMBL:EAL67787.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL67787.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL67787.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL67787.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000256|ARBA:ARBA00008655}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL67787.1}.
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DR EMBL; AAFI02000030; EAL67787.1; -; Genomic_DNA.
DR RefSeq; XP_641767.1; XM_636675.1.
DR AlphaFoldDB; Q54X10; -.
DR SMR; Q54X10; -.
DR STRING; 44689.Q54X10; -.
DR PaxDb; 44689-DDB0205694; -.
DR GeneID; 8621965; -.
DR KEGG; ddi:DDB_G0279277; -.
DR dictyBase; DDB_G0279277; -.
DR eggNOG; KOG2898; Eukaryota.
DR HOGENOM; CLU_062954_0_0_1; -.
DR InParanoid; Q54X10; -.
DR OMA; LWKNEIF; -.
DR PhylomeDB; Q54X10; -.
DR Reactome; R-DDI-1482788; Acyl chain remodelling of PC.
DR Reactome; R-DDI-1482801; Acyl chain remodelling of PS.
DR Reactome; R-DDI-1482839; Acyl chain remodelling of PE.
DR Reactome; R-DDI-1482925; Acyl chain remodelling of PG.
DR Reactome; R-DDI-1483166; Synthesis of PA.
DR Reactome; R-DDI-6798695; Neutrophil degranulation.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005811; C:lipid droplet; HDA:dictyBase.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042171; F:lysophosphatidic acid acyltransferase activity; IBA:GO_Central.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR23063:SF1; LYSOPHOSPHATIDIC ACID:OLEOYL-COA ACYLTRANSFERASE 1; 1.
DR PANTHER; PTHR23063; PHOSPHOLIPID ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..216
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF01553"
SQ SEQUENCE 361 AA; 40624 MW; 4A78D4AD84A98D94 CRC64;
MEKFSNWRDG PTGIHPLLPP KAKSVSVFGY IIKFVIGPII SIIRVPIILI LTALLIIFNI
IARSIPIGWL SRMICRFFDI IIGRIILLCM GFIQLDEFTE TLSRSKVASG SIDQCTRKDI
IICNHSSYVD IIYLCYKFSP TFAIPPNDEK NLNENIGKLI PLTLGRALEN SIYSPIQLSS
KSVDTNKLVE SIQSSWNGPL VIFPEGTTSN GQGLLDISPI FPSQSQSQSQ SQFNTFKEIS
ANKLSIHVIG LSYHYGIYSP CYSSVGNVFL HLFLVCCQIS NSIQIHYLSR SCMPPPPKQS
QLSQYINNNG LSDENEWFDQ LFKSLSSLIN TRRTKITNND KLSFISKWKG YKVDYSSKKS
N
//
