ID Q54YB5_DICDI Unreviewed; 997 AA.
AC Q54YB5;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Transcription factor IIIC-gamma subunit {ECO:0000313|EMBL:EAL68333.1};
GN Name=TFIIIC3 {ECO:0000313|EMBL:EAL68333.1};
GN ORFNames=DDB_G0278321 {ECO:0000313|EMBL:EAL68333.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL68333.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL68333.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL68333.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL68333.1}.
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DR EMBL; AAFI02000023; EAL68333.1; -; Genomic_DNA.
DR RefSeq; XP_642287.1; XM_637195.1.
DR AlphaFoldDB; Q54YB5; -.
DR SMR; Q54YB5; -.
DR STRING; 44689.Q54YB5; -.
DR PaxDb; 44689-DDB0231090; -.
DR GeneID; 8621494; -.
DR KEGG; ddi:DDB_G0278321; -.
DR dictyBase; DDB_G0278321; gtf3C3.
DR eggNOG; KOG2076; Eukaryota.
DR HOGENOM; CLU_002391_1_0_1; -.
DR InParanoid; Q54YB5; -.
DR OMA; SSPNMKF; -.
DR PhylomeDB; Q54YB5; -.
DR Reactome; R-DDI-76061; RNA Polymerase III Transcription Initiation From Type 1 Promoter.
DR Reactome; R-DDI-76066; RNA Polymerase III Transcription Initiation From Type 2 Promoter.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0000127; C:transcription factor TFIIIC complex; ISS:dictyBase.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR039340; Tfc4/TFIIIC-102/Sfc4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR23082:SF0; GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3; 1.
DR PANTHER; PTHR23082; TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 519..552
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 920..953
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..90
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 113952 MW; 116F87A3B9CF3A5E CRC64;
MTTEKSKDLK GLLNENDDDD EMPFNIEEIG IKIHDILVNI PPPSKETSSL NFQENLSEVE
ESSDSEDDKE ESDDDEEDDD EEDDDDDEGG ISKEEILRQS KNIAFPEQKA KKRPATPKIV
SVLSQKKVVD KADKFDMDTF KTTISGSTSK KKKSLLPTEQ DKEEERKRRE RDSDDDGNAD
DDDDDNDKMN IDSNNNNKTT TTTTTTTNKI PKKKKKKRFY SQQEIRIPKE VRKLLVGGNE
QYTKGNFDLA FSTYAEVVRM LPRLSIPYNI LGKIKESQGE MEAALGFYVY GAQMQGSNGD
WSSIGVRAKE AGQMETALYC FSRACRNDET DLDSFWEKSL ILIQKGFYKR ALKILTKLSK
YTNGSPQVLQ ELARVYSHLS QYHDASAMIS EVVDEQLLSN KSLDDVSLDS VNLMMELKNK
TRNYQDTITI FNKITAKYGN DSEVPFDLVF NACQAYYSLG TDFGNERGSK LLHLRLLPLD
PSEYGDLFTS LADELFALGK YQDALVVYLH LKDTDFDIPS NWVKIADIHR STKNYEVAIE
YFSKANERVP GNVHTTLAMS EIYKEMGDDE KALQILNQSS TISNRNDQSE KELFESTLNE
LNSKRNAYLN SIKNNSSTAA AAAAAAGGAT NTTSTSGAKE SNPVGLDVTK EDVKLFYRHA
QAFLNLSKYS QYLGIATALL HGSTDRYIYR RKVGVGKFKK RKRVKRSKNP YSIEMYKHQS
EHPYAELLDE EDYFNLLLDS SKIFVHLNRQ QEASQYLRYA LRNIHFENGL FSHQLKFLTV
AVAFNDKNYY LAYKHVKYVC SKKPYSNRVW NLFNKIIVNY GNRSTVQNRF LTKINEKYSD
SIPVLIMLGN QNKQTDNARG ALFEYIKAYR LCPDDPLINL LISVLILSQV MGRKQANRHR
IAITSYSFLY KYYNLRGKSQ ESLYNLGRGY HQLGIYNMAI NYYDMVLNYE DEIDEETGEI
NKNDSLKCEA AFNLSLIYKS KGNTSLANEI LKKYIVV
//
