ID Q54ZK5_DICDI Unreviewed; 982 AA.
AC Q54ZK5;
DT 24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 02-MAY-2006, sequence version 2.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=DDB_G0277521 {ECO:0000313|EMBL:EAL68723.2};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL68723.2, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL68723.2, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL68723.2,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL68723.2, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL68723.2,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL68723.2}.
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DR EMBL; AAFI02000020; EAL68723.2; -; Genomic_DNA.
DR RefSeq; XP_642637.2; XM_637545.2.
DR AlphaFoldDB; Q54ZK5; -.
DR SMR; Q54ZK5; -.
DR PaxDb; 44689-DDB0203383; -.
DR EnsemblProtists; EAL68723; EAL68723; DDB_G0277521.
DR GeneID; 8621054; -.
DR KEGG; ddi:DDB_G0277521; -.
DR dictyBase; DDB_G0277521; -.
DR eggNOG; KOG1075; Eukaryota.
DR HOGENOM; CLU_008798_0_0_1; -.
DR InParanoid; Q54ZK5; -.
DR OMA; IFHANRH; -.
DR PhylomeDB; Q54ZK5; -.
DR Proteomes; UP000002195; Chromosome 2.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR31635:SF196; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31635; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT DOMAIN 474..739
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 982 AA; 114378 MW; 8B183BA65EACF9C6 CRC64;
MIKIMTWNCQ GCSTIKSMNQ TKNTINLIKP DISILTETNL KKDQNLAQIK NHYSTGGKGK
EARGKGVMAI NHLEQIEIKN LEEKEGRILK FTAILNNTEI NIIGIYAPAS YDRRKGWFSN
NISLGDLEQA DIVTGDFNIN KYAKIKFKDG SSDKRKFTEN ETIEFLMMEV GLTEILPNST
TKTTFKDKLI DRTFLSTKMH QLNHSYKIID KINKSDHNIV VMDFKIPNFT KIYKSPLWKM
NSIIIKEDKT IKKIEKIIDH YQETKRKNLN ITEYWIKFKK KIKKQCITTE KKRILERKKT
LSNLANEHTK TKNKYEKETI SNEITILQEE ERIDRMIKSS INYINNKEIA SNLLTSILKK
RDSSSQIHRI KNPSNGEIET EQKEITDCFR KYYETLFKEK ECDQETHTEL LSTWNPPIDK
KKLTEMEDRI EEYEVKLAIE KIAEGKSPGE DGITSSFYKI HQHKLIPILT ELFNFFLNNE
IPTEFKNGIL TSIYKGKGDV LEISNRRPIT LLNVDYKIYS KIINNRILKI LPNIISKYQN
GFIPGRLLHN NIIALDLAME KSDRNTIITF YDFEKAFDSI SHKALIRTLN HLKFPRKITN
TILSMLTNTN IRVMVNGQLS ESFRAGRGTK QGDPISPTLF AIVCECLSTS IRKDNTIIGI
KLNQNNSMKI GQYADDTVTL ASNIDDADKM DMKVIKFCQA TAAKINDNKC VCITKNPKIK
TKYKTIGAKE EERYLGFFFN RKGVISKVDD TVNKLENLTK CYSSVSSTLK GRITILKSYL
LSQLTFQLYI NEINDIKKLE NVNANMLFKG DRWAISKERS RRDYEIGGLE LWNMATRSNA
QKAWIYEQYL REKDDQNCPP HMEVWKSEKE NSLSRIHIKC WKAWKLLHHP RERITLKLNQ
VKPKYENKQK LKVIYRNMMD IKYKGWNKHQ PTTGQKLIQK NINHPILPFR EARSITTIKG
RDLAWRYLLK ALPKHHGENC HL
//
