ID Q556I6_DICDI Unreviewed; 545 AA.
AC Q556I6; Q86K13;
DT 02-MAY-2006, integrated into UniProtKB/TrEMBL.
DT 02-MAY-2006, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN ORFNames=DDB_G0272612 {ECO:0000313|EMBL:EAL70943.1}, DDB_G0274027
GN {ECO:0000313|EMBL:EAL70447.1};
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689 {ECO:0000313|EMBL:EAL70447.1, ECO:0000313|Proteomes:UP000002195};
RN [1] {ECO:0000313|EMBL:EAL70447.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70447.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=12097910; DOI=10.1038/nature00847;
RG Dictyostelium Genome Sequencing Consortium;
RA Glockner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2] {ECO:0000313|EMBL:EAL70447.1, ECO:0000313|Proteomes:UP000002195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70447.1,
RC ECO:0000313|Proteomes:UP000002195};
RX PubMed=15875012; DOI=10.1038/nature03481;
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Glockner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M., Spiegler S., Tivey A., Sugano S.,
RA White B., Walker D., Woodward J., Winckler T., Tanaka Y., Shaulsky G.,
RA Schleicher M., Weinstock G., Rosenthal A., Cox E.C., Chisholm R.L.,
RA Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J., Dear P.H.,
RA Noegel A.A., Barrell B., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [3] {ECO:0000313|EMBL:EAL70447.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=AX4 {ECO:0000313|EMBL:EAL70447.1};
RG The Dictyostelium discoideum Sequencing Consortium;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.-A., Sucgang R.,
RA Song J., Cox E.C., Tunggal B., Szafranski K., Konfortov B.A.,
RA Farbrother P., Bankier A.T., Lehmann R., Hamlin N., Xu Q., Davies R.,
RA Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.,
RA Davis P., Nie X., Kerhornou A., Hemphill L., Bason N., Berriman M.,
RA Desany B., Churcher C., Cooper J., van Driessche N., Cronin A.,
RA Goodhead I., Muzny D., Hall N., Harper D., Lindsay R., Hauser H., James K.,
RA Quiles M., Buchrieser C., Wardroper A., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K., Price C., Ma J., Quail M.,
RA Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Weinstock G.,
RA Sharp S., Just E., Shaulsky G., Simmonds M., Tivey A., White B., Walker D.,
RA Woodward J., Winckler T., Schleicher M., Rosenthal A., Rivero F.,
RA Chisholm R.L., Gibbs R., Loomis W.F., Platzer M., Kay R.R., Williams J.,
RA Dear P.H., Noegel A.A., Barrell B., Kuspa A.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAL70447.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFI02000011; EAL70447.1; -; Genomic_DNA.
DR EMBL; AAFI02000009; EAL70943.1; -; Genomic_DNA.
DR RefSeq; XP_644372.1; XM_639280.1.
DR RefSeq; XP_645041.1; XM_639949.1.
DR AlphaFoldDB; Q556I6; -.
DR PaxDb; 44689-DDB0167972; -.
DR GeneID; 8618718; -.
DR GeneID; 8619258; -.
DR KEGG; ddi:DDB_G0272612; -.
DR KEGG; ddi:DDB_G0274027; -.
DR dictyBase; DDB_G0272612; -.
DR dictyBase; DDB_G0274027; -.
DR eggNOG; ENOG502RDMA; Eukaryota.
DR HOGENOM; CLU_500059_0_0_1; -.
DR OMA; NAGRGEW; -.
DR Proteomes; UP000002195; Chromosome 2.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR008999; Actin-crosslinking.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR37002; AGAP007005-PA; 1.
DR PANTHER; PTHR37002:SF3; TGC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF50405; Actin-crosslinking proteins; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002195}.
FT DOMAIN 405..469
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
FT REGION 149..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 60725 MW; 47F428C93BC97DAA CRC64;
MSVQLKDDLN FRLRSKKALK NKDGTDGWFL GVYDDGLISN GGNKSDKTIW VLKSVQSSFN
IISKDGNYCL GIDDGLNMIT NADPNGNGLF IFDWQPNGRV CIQSVFHASK KNRTGKFGPH
LGVDPQGGLI GNAGTGEWGQ WDIIPISEST TTVSHSSPDT TTTSTSSSSS SSKPSAPPSS
NDNKPTIVPS AHPSIKLLTD FAKHRELWGE QFYVEQKFTK TVDAKLKFMV RLPNLQVKKW
SVIACAPPSP LQTQMIKKAS LTIYDNTGNN EISKGQLIQA GSHYVMRAMV KGIAKQHKIH
AHYDIEADLY SISLKKIVPG QFMPMVQPLN PQERAYYLQT TNFINYNQPQ FQQWIRDNQL
HPMLLTDGTV ESVLCYAYRV FLFIKLHFDY VLAKDVLSGR KATDTINAKK SDCGGFSILY
SSILRMHGIP TRILIGRWAL SGTADKQKVH VVGEFYVDGC GWVPFDPACA ITADKTEPFT
KYFAQNSGEF ITMHVETGIH GIDNGIESKH QTIDFLQSIC YWVDGEGNFN NQESESLWTV
TPQQK
//
