ID Q567K3_DANRE Unreviewed; 437 AA.
AC Q567K3; A0A8M1N5G3;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=Zgc:111983 {ECO:0000313|EMBL:AAH93143.1, ECO:0000313|Ensembl:ENSDARP00000035524};
GN Name=wu:fi32a11 {ECO:0000313|RefSeq:NP_001017803.1};
GN ORFNames=zgc:111983 {ECO:0000313|EMBL:AAH93143.1,
GN ECO:0000313|Ensembl:ENSDARP00000035524,
GN ECO:0000313|RefSeq:NP_001017803.1,
GN ECO:0000313|ZFIN:ZDB-GENE-050417-335};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH93143.1};
RN [1] {ECO:0000313|EMBL:AAH93143.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium {ECO:0000313|EMBL:AAH93143.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|RefSeq:NP_001017803.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19308258;
RA Gomez G.A., Veldman M.B., Zhao Y., Burgess S., Lin S.;
RT "Discovery and characterization of novel vascular and hematopoietic genes
RT downstream of etsrp in zebrafish.";
RL PLoS ONE 4:E4994-E4994(2009).
RN [3] {ECO:0000313|RefSeq:NP_001017803.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22297719;
RA Mohseny A.B., Xiao W., Carvalho R., Spaink H.P., Hogendoorn P.C.,
RA Cleton-Jansen A.M.;
RT "An osteosarcoma zebrafish model implicates Mmp-19 and Ets-1 as well as
RT reduced host immune response in angiogenesis and migration.";
RL J. Pathol. 227:245-253(2012).
RN [4] {ECO:0000313|Ensembl:ENSDARP00000035524}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000035524};
RG Ensembl;
RL Submitted (FEB-2012) to UniProtKB.
RN [5] {ECO:0000313|Ensembl:ENSDARP00000035524, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000035524};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [6] {ECO:0000313|RefSeq:NP_001017803.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25692557;
RA Takamiya M., Weger B.D., Schindler S., Beil T., Yang L., Armant O.,
RA Ferg M., Schlunck G., Reinhard T., Dickmeis T., Rastegar S., Strahle U.;
RT "Molecular description of eye defects in the zebrafish Pax6b mutant,
RT sunrise, reveals a Pax6b-dependent genetic network in the developing
RT anterior chamber.";
RL PLoS ONE 10:e0117645-e0117645(2015).
RN [7] {ECO:0000313|RefSeq:NP_001017803.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=28242321;
RA Chatzopoulou A., Schoonheim P.J., Torraca V., Meijer A.H., Spaink H.P.,
RA Schaaf M.J.;
RT "Functional analysis reveals no transcriptional role for the glucocorticoid
RT receptor beta-isoform in zebrafish.";
RL Mol. Cell. Endocrinol. 447:61-70(2017).
RN [8] {ECO:0000313|RefSeq:NP_001017803.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL953855; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC093143; AAH93143.1; -; mRNA.
DR RefSeq; NP_001017803.1; NM_001017803.1.
DR STRING; 7955.ENSDARP00000035524; -.
DR PaxDb; 7955-ENSDARP00000035524; -.
DR Ensembl; ENSDART00000034549.7; ENSDARP00000035524.5; ENSDARG00000006588.9.
DR GeneID; 550501; -.
DR KEGG; dre:550501; -.
DR AGR; ZFIN:ZDB-GENE-050417-335; -.
DR ZFIN; ZDB-GENE-050417-335; zgc:111983.
DR eggNOG; KOG4297; Eukaryota.
DR HOGENOM; CLU_035816_0_0_1; -.
DR OMA; APRINNF; -.
DR OrthoDB; 4273158at2759; -.
DR TreeFam; TF343650; -.
DR Proteomes; UP000000437; Chromosome 1.
DR Bgee; ENSDARG00000006588; Expressed in pharyngeal gill and 25 other cell types or tissues.
DR InterPro; IPR000082; SEA_dom.
DR PANTHER; PTHR35193; MUCIN 13A, CELL SURFACE-ASSOCIATED-RELATED; 1.
DR PANTHER; PTHR35193:SF8; ZGC:111983-RELATED; 1.
DR Pfam; PF01390; SEA; 2.
DR PROSITE; PS50024; SEA; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q567K3};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001017803.1}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..437
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001017803.1"
FT /id="PRO_5035034232"
FT DOMAIN 168..279
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT REGION 29..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 44999 MW; 5BAFFFF4704AFFFA CRC64;
MEWRIILPVL CLIGILNLPG YVVSQQAVTP SATSTTTTTA TTTTTTTATT TATPTTSTTT
TTPTTSTAVT TTTTVPTSTT TATTHSSGAT TASTASGATT ASTASGATTA STASGATTAS
TASGATTAST ASGATTASTA SGATTASTAS GATTASTAGS QATTLPANVQ SVNLIFKIED
QFQAYYSDFT DPRTISYVQN ITAQFNTVYK KSYQNYIRMI IKKLSSGSVA ADADFQFNTS
ISSAPNATDA KNTLVQAINN KEFTFTINST SITTVDGSST TASPVTTQTT TVATTAVVLS
NYNITFKMAG VFFSDLANLN SKAGSLLSLA VSGQLNYFYS NFRGFNGANV WRFRNGSIYV
DALLVFIKNI NAPNATELAK ELGAAVRNQT IFLPIDPTTI NITDFTGFSA SKSPVLASML
TALWMTLASL LLSAVMH
//
