ID Q568N2_DANRE Unreviewed; 96 AA.
AC Q568N2; A0A0N4STW0; B2GSH8;
DT 10-MAY-2005, integrated into UniProtKB/TrEMBL.
DT 10-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 125.
DE SubName: Full=ADP ribosylation factor-like GTPase 3a {ECO:0000313|Ensembl:ENSDARP00000133017};
DE SubName: Full=ADP-ribosylation factor-like protein 3 isoform 2 {ECO:0000313|RefSeq:NP_001017827.1};
DE SubName: Full=ADP-ribosylation factor-like protein 3 isoform X1 {ECO:0000313|RefSeq:XP_009305435.1};
DE SubName: Full=Zgc:110197 {ECO:0000313|EMBL:AAH92789.1, ECO:0000313|EMBL:AAI65524.1};
GN Name=arl3a {ECO:0000313|Ensembl:ENSDARP00000133017,
GN ECO:0000313|ZFIN:ZDB-GENE-050417-368};
GN Synonyms=si:dkey-52k1.1 {ECO:0000313|RefSeq:NP_001017827.1,
GN ECO:0000313|RefSeq:XP_009305435.1};
GN ORFNames=zgc:110197 {ECO:0000313|EMBL:AAI65524.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI65524.1};
RN [1] {ECO:0000313|EMBL:AAI65524.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mixed tissue {ECO:0000313|EMBL:AAH92789.1}, and PCR rescue
RC {ECO:0000313|EMBL:AAI65524.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000133017, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133017};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|Ensembl:ENSDARP00000133017}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000133017};
RG Ensembl;
RL Submitted (OCT-2015) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:NP_001017827.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=27189481;
RA Pasquier J., Cabau C., Nguyen T., Jouanno E., Severac D., Braasch I.,
RA Journot L., Pontarotti P., Klopp C., Postlethwait J.H., Guiguen Y.,
RA Bobe J.;
RT "Gene evolution and gene expression after whole genome duplication in fish:
RT the PhyloFish database.";
RL BMC Genomics 17:368-368(2016).
RN [5] {ECO:0000313|RefSeq:NP_001017827.1, ECO:0000313|RefSeq:XP_009305435.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_009305435.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; CR792443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; FO082778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC092789; AAH92789.1; -; mRNA.
DR EMBL; BC165524; AAI65524.1; -; mRNA.
DR RefSeq; NP_001017827.1; NM_001017827.1.
DR RefSeq; XP_009305435.1; XM_009307160.3.
DR Ensembl; ENSDART00000158369; ENSDARP00000133017; ENSDARG00000056794.
DR Ensembl; ENSDART00000158369.2; ENSDARP00000133017.1; ENSDARG00000056794.7.
DR GeneID; 550525; -.
DR KEGG; dre:550525; -.
DR AGR; ZFIN:ZDB-GENE-050417-368; -.
DR CTD; 550525; -.
DR ZFIN; ZDB-GENE-050417-368; arl3a.
DR HOGENOM; CLU_040729_14_2_1; -.
DR OrthoDB; 5349301at2759; -.
DR Proteomes; UP000000437; Chromosome 13.
DR Bgee; ENSDARG00000056794; Expressed in testis and 22 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR044612; ARL2/3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR PANTHER; PTHR45697; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR45697:SF4; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3; 1.
DR Pfam; PF00025; Arf; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q568N2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
SQ SEQUENCE 96 AA; 10677 MW; B2FDA99B79324021 CRC64;
MLIYVIDSAD RKRFEETGQE LAELLDEEKL SGVPVLIFAN KQDLLTAAPA SEIAEGLNLH
IIRDRMWQIQ SCSALTGEGV QDGMSWVCKN VTAKKK
//
